Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A024R0A8 | AHCYL1; hCG_38162 | Adenosylhomocysteinase (EC 3.13.2.1) | Homo sapiens (Human) | 530 aa |
Protein Details: A0A024R0A8 (AHCYL1)
Protein Information
| Accession | A0A024R0A8 |
|---|---|
| Protein Names | Adenosylhomocysteinase (EC 3.13.2.1) |
| Gene Symbol | AHCYL1; hCG_38162 |
| Organism | Homo sapiens (Human) |
| Length | 530 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 0.500
4/4 (100.0%)
3
PC3 cells
Specificity: 0.375
3/4 (75.0%)
1
Prefrontal cortex
Specificity: 0.125
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSMPDAMPLP11GVGEELKQAK21EIEDAEKYSF31MATVTKAPKK41QIQFADDMQE
51-10051FTKFPTKTGR61RSLSRSISQS71STDSYSSAAS81YTDSSDDEVS91PREKQQTNSK
101-150101GSSNFCVKNI111KQAEFGRREI121EIAEQDMSAL131ISLRKRAQGE141KPLAGAKIVG
151-200151CTHITAQTAV161LIETLCALGA171QCRWSACNIY181STQNEVAAAL191AEAGVAVFAW
201-250201KGESEDDFWW211CIDRCVNMDG221WQANMILDDG231GDLTHWVYKK241YPNVFKKIRG
251-300251IVEESVTGVH261RLYQLSKAGK271LCVPAMNVND281SVTKQKFDNL291YCCRESILDG
301-350301LKRTTDVMFG311GKQVVVCGYG321EVGKGCCAAL331KALGAIVYIT341EIDPICALQA
351-400351CMDGFRVVKL361NEVIRQVDVV371ITCTGNKNVV381TREHLDRMKN391SCIVCNMGHS
401-450401NTEIDVTSLR411TPELTWERVR421SQVDHVIWPD431GKRVVLLAEG441RLLNLSCSTV
451-500451PTFVLSITAT461TQALALIELY471NAPEGRYKQD481VYLLPKKMDE491YVASLHLPSF
501-530501DAHLTELTDD511QAKYLGLNKN521GPFKPNYYRY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 106 | Prediction (Medium) | - | - |
| 151 | Prediction (Medium) | - | - |
| 166 | Prediction (Medium) | - | - |
| 172 | Prediction (Low) | - | - |
| 177 | Prediction (Medium) | - | - |
| 272 | Prediction (High) | - | - |
| 292 | Prediction (High) | - | - |
| 293 | Prediction (High) | - | - |
| 326 | Prediction (Medium) | - | - |
| 327 | Prediction (Medium) | - | - |
| 351 | Prediction (Medium) | - | - |
| 373 | Prediction (High) | - | - |
| 392 | Prediction (Low) | - | - |
| 447 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 292 | C → W | 0.002033 | SNP | Missense Mutation | LUSC |
| 441 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 392* | C → ? | 0.002545 | SNP | Nonsense Mutation | GBM |