Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A024R0Y5 PFKM; hCG_27714 6-phosphofructokinase type A (Phosphofructo-1-kinase isozyme … Homo sapiens (Human) 780 aa

Protein Details: A0A024R0Y5 (PFKM)

Protein Information
Accession A0A024R0Y5
Protein Names 6-phosphofructokinase type A (Phosphofructo-1-kinase isozyme A)
Gene Symbol PFKM; hCG_27714
Organism Homo sapiens (Human)
Length 780 aa
Isoforms No isoforms
Related PMIDs 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 1.000
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTHEEHHAAK11TLGIGKAIAV21LTSGGDAQGM31NAAVRAVVRV41GIFTGARVFF
51-10051VHEGYQGLVD61GGDHIKEATW71ESVSMMLQLG81GTVIGSARCK91DFREREGRLR
101-150101AAYNLVKRGI111TNLCVIGGDG121SLTGADTFRS131EWSDLLSDLQ141KAGKITDEEA
151-200151TKSSYLNIVG161LVGSIDNDFC171GTDMTIGTDS181ALHRIMEIVD191AITTTAQSHQ
201-250201RTFVLEVMGR211HCGYLALVTS221LSCGADWVFI231PECPPDDDWE241EHLCRRLSET
251-300251RTRGSRLNII261IVAEGAIDKN271GKPITSEDIK281NLVVKRLGYD291TRVTVLGHVQ
301-350301RGGTPSAFDR311ILGSRMGVEA321VMALLEGTPD331TPACVVSLSG341NQAVRLPLME
351-400351CVQVTKDVTK361AMDEKKFDEA371LKLRGRSFMN381NWEVYKLLAH391VRPPVSKSGS
401-450401HTVAVMNVGA411PAAGMNAAVR421STVRIGLIQG431NRVLVVHDGF441EGLAKGQIEE
451-500451AGWSYVGGWT461GQGGSKLGTK471RTLPKKSFEQ481ISANITKFNI491QGLVIIGGFE
501-550501AYTGGLELME511GRKQFDELCI521PFVVIPATVS531NNVPGSDFSV541GADTALNTIC
551-600551TTCDRIKQSA561AGTKRRVFII571ETMGGYCGYL581ATMAGLAAGA591DAAYIFEEPF
601-650601TIRDLQANVE611HLVQKMKTTV621KRGLVLRNEK631CNENYTTDFI641FNLYSEEGKG
651-700651IFDSRKNVLG661HMQQGGSPTP671FDRNFATKMG681AKAMNWMSGK691IKESYRNGRI
701-750701FANTPDSGCV711LGMRKRALVF721QPVAELKDQT731DFEHRIPKEQ741WWLKLRPILK
751-780751ILAKYEIDLD761TSDHAHLEHI771TRKRSGEAAV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
89 Prediction (Low) - -
114 Prediction (Medium) - -
170 Prediction (Low) - -
212 Prediction (Low) - -
244 Prediction (Low) - -
351 Prediction (High) - -
550 Prediction (Medium) - -
553 Prediction (Medium) - -
709 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
89 C → Afs*18 0.001969 DEL Frame Shift Del HNSC
286 R → C 0.001887 SNP Missense Mutation UCEC
414 G → C 0.002288 SNP Missense Mutation STAD
420 R → C 0.002545 SNP Missense Mutation GBM
459 W → C 0.002294 SNP Missense Mutation OV
565 R → C 0.001887 SNP Missense Mutation UCEC
686 W → C 0.002506 SNP Missense Mutation COAD
702 A → Cfs*14 0.001887 INS Frame Shift Ins UCEC
714 R → C 0.001014 SNP Missense Mutation BRCA