Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A087WW66 | PSMD1 | 26S proteasome non-ATPase regulatory subunit … | Homo sapiens (Human) | 914 aa |
Protein Details: A0A087WW66 (PSMD1)
Protein Information
| Accession | A0A087WW66 |
|---|---|
| Protein Names | 26S proteasome non-ATPase regulatory subunit 1 |
| Gene Symbol | PSMD1 |
| Organism | Homo sapiens (Human) |
| Length | 914 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MITSAAGIIS11LLDEDEPQLK21EFALHKLNAV31VNDFWAEISE41SVDKIEVLYE
51-10051DEGFRSRQFA61ALVASKVFYH71LGAFEESLNY81ALGAGDLFNV91NDNSEYVETI
101-150101IAKCIDHYTK111QCVENADLPE121GEKKPIDQRL131EGIVNKMFQR141CLDDHKYKQA
151-200151IGIALETRRL161DVFEKTILES171NDVPGMLAYS181LKLCMSLMQN191KQFRNKVLRV
201-250201LVKIYMNLEK211PDFINVCQCL221IFLDDPQAVS231DILEKLVKED241NLLMAYQICF
251-300251DLYESASQQF261LSSVIQNLRT271VGTPIASVPG281STNTGTVPGS291EKDSDSMETE
301-350301EKTSSAFVGK311TPEASPEPKD321QTLKMIKILS331GEMAIELHLQ341FLIRNNNTDL
351-400351MILKNTKDAV361RNSVCHTATV371IANSFMHCGT381TSDQFLRDNL391EWLARATNWA
401-450401KFTATASLGV411IHKGHEKEAL421QLMATYLPKD431TSPGSAYQEG441GGLYALGLIH
451-500451ANHGGDIIDY461LLNQLKNASN471DIVRHGGSLG481LGLAAMGTAR491QDVYDLLKTN
501-550501LYQDDAVTGE511AAGLALGLVM521LGSKNAQAIE531DMVGYAQETQ541HEKILRGLAV
551-600551GIALVMYGRM561EEADALIESL571CRDKDPILRR581SGMYTVAMAY591CGSGNNKAIR
601-650601RLLHVAVSDV611NDDVRRAAVE621SLGFILFRTP631EQCPSVVSLL641SESYNPHVRY
651-700651GAAMALGICC661AGTGNKVNQF671RQLYSKVIND681KHDDVMAKFG691AILAQGILDA
701-750701GGHNVTISLQ711SRTGHTHMPS721VVGVLVFTQF731WFWFPLSHFL741SLAYTPTCVI
751-800751GLNKDLKMPK761VQYKSNCKPS771TFAYPAPLEV781PKEKEKEKVS791TAVLSITAKA
801-850801KKKEKEKEKK811EEEKMEVDEA821EKKEEKEKKK831EPEPNFQLLD841NPARVMPAQL
851-900851KVLTMPETCR861YQPFKPLSIG871GIIILKDTSE881DIEELVEPVA891AHGPKIEEEE
901-914901QEPEPPEPFE911YIDD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 104 | - | - | - |
Deep-Palm: 0.04
|
|
| 112 | - | - | - |
Deep-Palm: 0.62
|
|
| 141 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.81
|
|
| 184 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.87
|
|
| 217 | - | - | - |
Deep-Palm: 0.47
|
|
| 219 | - | - | - |
Deep-Palm: 0.67
|
|
| 249 | - | - | - |
Deep-Palm: 0.79
|
|
| 365 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.56
|
|
| 378 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.46
|
|
| 571 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.86
Deep-Palm: 0.95
|
|
| 591 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.96
|
|
| 633 | HEAT repeats |
HeLa
(29575903)
|
Unknown
(32651440)
|
GPS-Palm: 0.79
Deep-Palm: 0.96
|
|
| 659 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.87
|
|
| 660 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.91
|
|
| 748 | - | - | - |
Deep-Palm: 0.87
|
|
| 767 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.72
|
|
| 859 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.500
4/4 (100.0%)
1
LNCaP
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Cerebral Cortex (Mass)
Specificity: 0.375
3/4 (75.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 69 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 480 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 546 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 572 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 802 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 910 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |