Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A087WY71 | AP2M1 | AP-2 complex subunit mu | Homo sapiens (Human) | 434 aa |
Protein Details: A0A087WY71 (AP2M1)
Protein Information
| Accession | A0A087WY71 |
|---|---|
| Protein Names | AP-2 complex subunit mu |
| Gene Symbol | AP2M1 |
| Organism | Homo sapiens (Human) |
| Length | 434 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.795
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.795
35/46 (76.1%)
4
PC3 cells
Specificity: 0.091
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.091
4/4 (100.0%)
1
Prefrontal cortex
Specificity: 0.023
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MIGGLFIYNH11KGEVLISRVY21RDDIGRNAVD31AFRVNVIHAR41QQVRSPVTNI
51-10051ARTSFFHVKR61SNIWLAAVTK71QNVNAAMVFE81FLYKMCDVMA91AYFGKISEEN
101-150101IKNNFVLIYE111LLDEILDFGY121PQNSETGALK131TFITQQGIKS141QHTKEEQSQI
151-200151TSQVTGQIGW161RREGIKYRRN171ELFLDVLESV181NLLMSPQGQV191LSAHVSGRVV
201-250201MKSYLSGMPE211CKFGMNDKIV221IEKQGKGTAD231ETSKSGKQSI241AIDDCTFHQC
251-300251VRLSKFDSER261SISFIPPDGE271FELMRYRTTK281DIILPFRVIP291LVREVGRTKL
301-350301EVKVVIKSNF311KPSLLAQKIE321VRIPTPLNTS331GVQVICMKGK341AKYKASENAI
351-400351VWKIKRMAGM361KESQISAEIE371LLPTNDKKKW381ARPPISMNFE391VPFAPSGLKV
401-434401RYLKVFEPKL411NYSDHDVIKW421VRYIGRSGIY431ETRC
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 336 | Prediction (High) | - | - |
| 434 | Prediction (High) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 44 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 44 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 83 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 246 | C → Y | 0.002747 | SNP | Missense Mutation | LIHC |
| 251 | C → C | 0.002033 | SNP | Silent | LUSC |
| 278 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 298 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 397 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 423 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |