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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A087X1K9 LYPLA1 Acyl-protein thioesterase 1 (EC 3.1.2.22) … Homo sapiens (Human) 166 aa

Protein Details: A0A087X1K9 (LYPLA1)

Protein Information
AccessionA0A087X1K9
Protein NamesAcyl-protein thioesterase 1 (EC 3.1.2.22) (Lysophospholipase 1) (Lysophospholipase I) (Palmitoyl-protein hydrolase)
Gene SymbolLYPLA1
OrganismHomo sapiens (Human)
Length166 aa
IsoformsNo isoforms
Related PMIDs 31251020
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNVAMPSWFD11IIGLSPDSQE21DESGIKQAAE31NIKALIDQEV41KNGIPSNRII
51-10051LGGFSQGGAL61SLYTALTTQQ71KLAGVTALSC81WLPLRASFPQ91GPIGGANRDI
101-150101SILQCHGDCD111PLVPLMFGSL121TVEKLKTLVN131PANVTFKTYE141GMMHSSCQQE
151-166151MMDVKQFIDK161LLPPID
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
80 SWISSPALM DBPTM CYSMODDB Phospholipase/Carboxylesterase
HeLa (29575903)
Unknown (32651440)
Deep-Palm: 0.97
105 - - -
Deep-Palm: 0.82
109 - - -
Deep-Palm: 0.79
147 - - -
Deep-Palm: 0.28
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.