Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A087X2I1 | PSMC6 | 26S proteasome regulatory subunit 10B … | Homo sapiens (Human) | 403 aa |
Protein Details: A0A087X2I1 (PSMC6)
Protein Information
| Accession | A0A087X2I1 |
|---|---|
| Protein Names | 26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42) |
| Gene Symbol | PSMC6 |
| Organism | Homo sapiens (Human) |
| Length | 403 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.750
3/4 (75.0%)
1
U937 cells
Specificity: 0.250
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAIPGIPYER11RLLIMADPRD21KALQDYRKKL31LEHKEIDGRL41KELREQLKEL
51-10051TKQYEKSEND61LKALQSVGQI71VGEVLKQLTE81EKFIVKATNG91PRYVVGCRRQ
101-150101LDKSKLKPGT111RVALDMTTLT121IMRYLPREVD131PLVYNMSHED141PGNVSYSEIG
151-200151GLSEQIRELR161EVIELPLTNP171ELFQRVGIIP181PKGCLLYGPP191GTGKTLLARA
201-250201VASQLDCNFL211KVVSSSIVDK221YIGESARLIR231EMFNYARDHQ241PCIIFMDEID
251-300251AIGGRRFSEG261TSADREIQRT271LMELLNQMDG281FDTLHRVKMI291MATNRPDTLD
301-350301PALLRPGRLD311RKIHIDLPNE321QARLDILKIH331AGPITKHGEI341DYEAIVKLSD
351-400351GFNGADLRNV361CTEAGMFAIR371ADHDFVVQED381FMKAVRKVAD391SKKLESKLDY
401-403401KPV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 97 | Prediction (Medium) | - | - |
| 184 | Prediction (Medium) | - | - |
| 207 | Prediction (Medium) | - | - |
| 361 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 161 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 177 | G → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 213 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 241 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 291 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 356 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |