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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A087X2I1 PSMC6 26S proteasome regulatory subunit 10B … Homo sapiens (Human) 403 aa

Protein Details: A0A087X2I1 (PSMC6)

Protein Information
AccessionA0A087X2I1
Protein Names26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)
Gene SymbolPSMC6
OrganismHomo sapiens (Human)
Length403 aa
IsoformsNo isoforms
Related PMIDs 31382980
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAIPGIPYER11RLLIMADPRD21KALQDYRKKL31LEHKEIDGRL41KELREQLKEL
51-10051TKQYEKSEND61LKALQSVGQI71VGEVLKQLTE81EKFIVKATNG91PRYVVGCRRQ
101-150101LDKSKLKPGT111RVALDMTTLT121IMRYLPREVD131PLVYNMSHED141PGNVSYSEIG
151-200151GLSEQIRELR161EVIELPLTNP171ELFQRVGIIP181PKGCLLYGPP191GTGKTLLARA
201-250201VASQLDCNFL211KVVSSSIVDK221YIGESARLIR231EMFNYARDHQ241PCIIFMDEID
251-300251AIGGRRFSEG261TSADREIQRT271LMELLNQMDG281FDTLHRVKMI291MATNRPDTLD
301-350301PALLRPGRLD311RKIHIDLPNE321QARLDILKIH331AGPITKHGEI341DYEAIVKLSD
351-400351GFNGADLRNV361CTEAGMFAIR371ADHDFVVQED381FMKAVRKVAD391SKKLESKLDY
401-403401KPV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
97 - - -
Deep-Palm: 0.97
184 - - -
Deep-Palm: 0.97
207 - -
Unknown (32651440)
Deep-Palm: 0.98
242 - - -
Deep-Palm: 0.23
361 - - -
Deep-Palm: 0.86
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
U937 cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
161 R → C 0.001887 SNP Missense Mutation UCEC
177 G → C 0.002427 SNP Missense Mutation BLCA
213 R → C 0.001887 SNP Missense Mutation UCEC
241 R → C 0.001887 SNP Missense Mutation UCEC
291 R → C 0.003460 SNP Missense Mutation CESC
356 R → C 0.002141 SNP Missense Mutation SKCM