Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A0B4J2A4 | ACAA2 | Acetyl-CoA acyltransferase 2 | Homo sapiens (Human) | 394 aa |
Protein Details: A0A0B4J2A4 (ACAA2)
Protein Information
| Accession | A0A0B4J2A4 |
|---|---|
| Protein Names | Acetyl-CoA acyltransferase 2 |
| Gene Symbol | ACAA2 |
| Organism | Homo sapiens (Human) |
| Length | 394 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
2
PC3 cells
Specificity: 0.500
2/4 (50.0%)
1
U937 cells
Specificity: 0.250
1/1 (100.0%)
1
HeLa cells
Specificity: 0.250
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MMGVFVVAAK11RTPFGAYGGL21LKDFTATDLS31EFAAKAALSA41GKVSPETVDS
51-10051VIMGNVLQSS61SDAIYLARHV71GLRVGIPKET81PALTINRLCG91SGFQSIVNGC
101-150101QEICVKEAEV111VLCGGTESMS121QAPYCVRNVR131FGTKLGSDIK141LEDSLWVSLT
151-200151DQHVQLPMAM161TAENLAVKHK171ISREECDKYA181LQSQQRWKAA191NDAGYFNDEM
201-250201APIEVKTKKG211KQTMQVDEHA221RPQTTLEQLQ231KLPPVFKKDG241TVTAGNASGV
251-300251ADGAGAVIIA261SEDAVKKHNF271TPLARIVGYF281VSGCDPSIMG291IGPVPAISGA
301-350301LKKAGLSLKD311MDLVEVNEAF321APQYLAVERS331LDLDISKTNV341NGGAIALGHP
351-394351LGGSGSRITA361HLVHELRRRG371GKYAVGSACI381GGGQGIAVII391QSTA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 89 | Prediction (Medium) | - | - |
| 125 | Prediction (High) | - | - |
| 176 | Experimental | Thiolase N-terminal domain | 29575903 |
| 284 | Prediction (Low) | - | - |
| 379 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 76 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 371 | R → C | 0.001969 | SNP | Missense Mutation | LGG |