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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A0G2JH50 HLA-C Major histocompatibility complex, class I, … Homo sapiens (Human) 372 aa

Protein Details: A0A0G2JH50 (HLA-C)

Protein Information
Accession A0A0G2JH50
Protein Names Major histocompatibility complex, class I, C
Gene Symbol HLA-C
Organism Homo sapiens (Human)
Length 372 aa
Isoforms No isoforms
Related PMIDs 19801377 22496122 29575903 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.429
3/4 (75.0%)
2
DU145 cells
Specificity: 0.286
2/2 (100.0%)
1
HeLa cells
Specificity: 0.143
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.143
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRVMAPRTLI11LLLSGALALT21ETWACSHSMR31YFYTAVSRPG41RGEPRFIAVG
51-10051YVDDTQFVQF61DSDAASPRGE71PRAPWVEQEG81PEYWDRETQK91YKRQAQTDRV
101-150101NLRKLRGYYN111QSEAGSHTLQ121RMYGCDLGPD131GRLLRGYNQF141AYDGKDYIAL
151-200151NEDLRSWTAA161DKAAQITQRK171WEAAREAEQR181RAYLEGTCVE191WLRRYLENGK
201-250201KTLQRAEHPK211THVTHHPVSD221HEATLRCWAL231GFYPAEITLT241WQRDGEDQTQ
251-300251DTELVETRPA261GDGTFQKWAA271VVVPSGEEQR281YTCHVQHEGL291PEPLTLRWGP
301-350301SSQPTIPIVG311IVAGLAVLAV321LAVLGAVMAV331VMCRRKSSGH341FLPTGGKGGS
351-372351CSQAASSNSA361QGSDESLIAC371KA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
25 Prediction (Low) - -
125 Prediction (High) - -
188 Prediction (Low) - -
283 CYSMODDB SWISSPALM DBPTM - -
333 Prediction (High) - -
370 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
233 Y → C 0.001887 SNP Missense Mutation UCEC
283 C → C 0.002545 SNP Silent GBM
298 W → C 0.002141 SNP Missense Mutation SKCM