Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A0G2JI89 | ABHD16A | Abhydrolase domain containing 16A, phospholipase | Homo sapiens (Human) | 263 aa |
Protein Details: A0A0G2JI89 (ABHD16A)
Protein Information
| Accession | A0A0G2JI89 |
|---|---|
| Protein Names | Abhydrolase domain containing 16A, phospholipase |
| Gene Symbol | ABHD16A |
| Organism | Homo sapiens (Human) |
| Length | 263 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPPPALFLSS11LYPRLEFQND21FYRSCIRRSS31PQPPPNLAWR41PESLYSGELA
51-10051GGGYLSLSKV61VPFSHYAGTL71LLLLAGVACL81RGIGRWTNPQ91YRQFITILEA
101-150101THRNQSSENK111RQLANYNFDF121RSWPVDFHWE131EPSSRKESRG141GPSRRGVALL
151-200151RPEPLHRGTA161DTLLNRVKKL171PCQITSYLVA181HTLGRRMLYP191GSVYLLQKAL
201-250201MPVLLQGQAR211LVEECNGRRA221KLLACDGNEI231DTMFVDRRGT241AEPQGQKLVI
251-263251CCEGNAGFYE261VGC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 25 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.64
|
|
| 79 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 172 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.97
|
| 215 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.98
|
|
| 225 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.81
Deep-Palm: 0.96
|
|
| 251 | - | - | - |
Deep-Palm: 0.21
|
|
| 252 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.07
|
|
| 263 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
PC3
Specificity: 0.400
4/4 (100.0%)
3
LNCaP
Specificity: 0.300
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Cerebral Cortex (Mass)
Specificity: 0.200
2/4 (50.0%)
1
LNCaP cells (Mass)
Specificity: 0.100
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 51 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 68 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 177 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 321 | V → Cfs*22 | 0.004577 | DEL | Frame Shift Del | STAD |