Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A0G2JIF0 | HLA-C | Major histocompatibility complex, class I, … | Homo sapiens (Human) | 368 aa |
Protein Details: A0A0G2JIF0 (HLA-C)
Protein Information
| Accession | A0A0G2JIF0 |
|---|---|
| Protein Names | Major histocompatibility complex, class I, C |
| Gene Symbol | HLA-C |
| Organism | Homo sapiens (Human) |
| Length | 368 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 22496122 29575903 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.429
3/4 (75.0%)
2
DU145 cells
Specificity: 0.286
2/2 (100.0%)
1
HeLa cells
Specificity: 0.143
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.143
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRVMAPRTLI11LLLSGALALT21ETWACSHSMR31YFYTAVSRPG41RGEPRFIAVG
51-10051YVDDTQFVQF61DSDAASPRGE71PRAPWVEQEG81PEYWDRETQK91YKRQAQTDRV
101-150101NLRKLRGYYN111QSEAGSHTLQ121RMYGCDLGPD131GRLLRGYNQF141AYDGKDYIAL
151-200151NEDLRSWTAA161DKAAQITQRK171WEAAREAEQR181RAYLEGTCVE191WLRRYLENGK
201-250201KTLQRAEHPK211THVTHHPVSD221HEATLRCWAL231GFYPAEITLT241WQRDGEDQTQ
251-300251DTELVETRPA261GDGTFQKWAA271VVVPSGEEQR281YTCHVQHEGL291PEPLTLRWGP
301-350301SSQPTIPIVG311IVAGLAVLAV321LAVLGAVMAV331VMCRRKSSAA341CVGLRCRISS
351-368351HLSFVTSRAS361GISFCKGI
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 25 | Prediction (Low) | - | - |
| 125 | Prediction (High) | - | - |
| 188 | Prediction (Low) | - | - |
| 283 | CYSMODDB SWISSPALM DBPTM | - | - |
| 333 | Prediction (High) | - | - |
| 341 | Prediction (High) | - | - |
| 346 | Prediction (Low) | - | - |
| 365 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 233 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 283 | C → C | 0.002545 | SNP | Silent | GBM |
| 298 | W → C | 0.002141 | SNP | Missense Mutation | SKCM |