Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A0G2JJD3 | ABHD16A | Phosphatidylserine lipase ABHD16A (EC 3.1.1.23) … | Homo sapiens (Human) | 601 aa |
Protein Details: A0A0G2JJD3 (ABHD16A)
Protein Information
| Accession | A0A0G2JJD3 |
|---|---|
| Protein Names | Phosphatidylserine lipase ABHD16A (EC 3.1.1.23) (Alpha/beta hydrolase domain-containing protein 16A) (Monoacylglycerol lipase ABHD16A) |
| Gene Symbol | ABHD16A |
| Organism | Homo sapiens (Human) |
| Length | 601 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSQLARRRSR11YGLTSRAHNT21SEAGRAGPAG31GPAAGRAAAR41AGAMAKLLSC
51-10051VLGPRLYKIY61RERDSERAPA71SVPETPTAVT81APHSSSWDTY91YQPRALEKHA
101-150101DSILALASVF111WSISYYSSPF121AFFYLYRKGY131LSLSKVVPFS141HYAGTLLLLL
151-200151AGVACLRGIG161RWTNPQYRQF171ITILEATHRN181QSSENKRQLA191NYNFDFRSWP
201-250201VDFHWEEPSS211RKESRGGPSR221RGVALLRPEP231LHRGTADTLL241NRVKKLPCQI
251-300251TSYLVAHTLG261RRMLYPGSVY271LLQKALMPVL281LQGQARLVEE291CNGRRAKLLA
301-350301CDGNEIDTMF311VDRRGTAEPQ321GQKLVICCEG331NAGFYEVGCV341STPLEAGYSV
351-400351LGWNHPGFAG361STGVPFPQNE371ANAMDVVVQF381AIHRLGFQPQ391DIIIYAWSIG
401-450401GFTATWAAMS411YPDVSAMILD421ASFDDLVPLA431LKVMPDSWRG441LVTRTVRQHL
451-500451NLNNAEQLCR461YQGPVLLIRR471TKDEIITTTV481PEDIMSNRGN491DLLLKLLQHR
501-550501YPRVMAEEGL511RVVRQWLEAS521SQLEEASIYS531RWEVEEDWCL541SVLRSYQAEH
551-600551GPDFPWSVGE561DMSADGRRQL571ALFLARKHLH581NFEATHCTPL591PAQNFQMPWH
601-601601L
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 50 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.97
Deep-Palm: 0.98
|
|
| 155 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 248 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.97
|
| 291 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.98
|
|
| 301 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.81
Deep-Palm: 0.96
|
|
| 327 | - | - | - |
Deep-Palm: 0.80
|
|
| 328 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.78
|
|
| 339 | - | - | - |
Deep-Palm: 0.63
|
|
| 459 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.86
Deep-Palm: 0.83
|
|
| 539 | - | - | - |
Deep-Palm: 0.81
|
|
| 587 | - | - | - |
Deep-Palm: 0.13
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
1
U937 cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
LNCaP cells (Mass)
Specificity: 0.250
2/4 (50.0%)
2
Cerebral Cortex (Mass)
Specificity: 0.250
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 51 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 68 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 177 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 321 | V → Cfs*22 | 0.004577 | DEL | Frame Shift Del | STAD |