Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A0S2Z3H0 | ATP2A2 | ATPase Ca++ transporting cardiac muscle … | Homo sapiens (Human) | 63 aa |
Protein Details: A0A0S2Z3H0 (ATP2A2)
Protein Information
| Accession | A0A0S2Z3H0 |
|---|---|
| Protein Names | ATPase Ca++ transporting cardiac muscle slow twitch 2 isoform 3 |
| Gene Symbol | ATP2A2 |
| Organism | Homo sapiens (Human) |
| Length | 63 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MENAHTKTVE11EVLGHFGVNE21STGLSLEQVK31KLKERWGSFP41LLGYWLLRRR
51-6351CYRGCCCMVV61HCC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 51 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.04
|
|
| 55 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.02
|
|
| 56 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.02
|
|
| 57 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.02
|
|
| 62 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
|
| 63 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
PC3
Specificity: 0.444
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
1
frontal cortex
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 256 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 349 | C → Kfs*17 | 0.001887 | DEL | Frame Shift Del | UCEC |
| 407 | Y → C | 0.002033 | SNP | Missense Mutation | THCA |
| 434 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 487 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 730 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 835 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 901 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 909 | C → C | 0.001969 | SNP | Silent | LGG |
| 914 | S → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1027 | I → Cfs*4 | 0.002506 | INS | Frame Shift Ins | COAD |
| 1028 | W → C | 0.001969 | SNP | Missense Mutation | HNSC |