Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A0S2Z489 PSMD12; hCG_1749256 26S proteasome non-ATPase regulatory subunit … Homo sapiens (Human) 456 aa

Protein Details: A0A0S2Z489 (PSMD12)

Protein Information
Accession A0A0S2Z489
Protein Names 26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
Gene Symbol PSMD12; hCG_1749256
Organism Homo sapiens (Human)
Length 456 aa
Isoforms No isoforms
Related PMIDs 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
PC3 cells
Specificity: 1.000
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADGGSERAD11GRIVKMEVDY21SATVDQRLPE31CAKLAKEGRL41QEVIETLLSL
51-10051EKQTRTASDM61VSTSRILVAV71VKMCYEAKEW81DLLNENIMLL91SKRRSQLKQA
101-150101VAKMVQQCCT111YVEEITDLPI121KLRLIDTLRM131VTEGKIYVEI141ERARLTKTLA
151-200151TIKEQNGDVK161EAASILQELQ171VETYGSMEKK181ERVEFILEQM191RLCLAVKDYI
201-250201RTQIISKKIN211TKFFQEENTE221KLKLKYYNLM231IQLDQHEGSY241LSICKHYRAI
251-300251YDTPCIQAES261EKWQQALKSV271VLYVILAPFD281NEQSDLVHRI291SGDKKLEEIP
301-350301KYKDLLKLFT311TMELMRWSTL321VEDYGMELRK331GSLESPATDV341FGSTEEGEKR
351-400351WKDLKNRVVE361HNIRIMAKYY371TRITMKRMAQ381LLDLSVDESE391AFLSNLVVNK
401-450401TIFAKVDRLA411GIINFQRPKD421PNNLLNDWSQ431KLNSLMSLVN441KTTHLIAKEE
451-456451MIHNLQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
31 Prediction (Medium) - -
74 Prediction (Medium) - -
108 Prediction (Low) - -
109 Prediction (Medium) - -
193 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
142 R → C 0.001887 SNP Missense Mutation UCEC
227 Y → C 0.002747 SNP Missense Mutation LIHC
242 S → C 0.002033 SNP Missense Mutation LUSC
316 R → C 0.002427 SNP Missense Mutation BLCA
342 G → C 0.003460 SNP Missense Mutation CESC