Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A0U1RQU3 | ATP2B1 | ATPase plasma membrane Ca2+ transporting … | Homo sapiens (Human) | 300 aa |
Protein Details: A0A0U1RQU3 (ATP2B1)
Protein Information
| Accession | A0A0U1RQU3 |
|---|---|
| Protein Names | ATPase plasma membrane Ca2+ transporting 1 |
| Gene Symbol | ATP2B1 |
| Organism | Homo sapiens (Human) |
| Length | 300 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XEKFFDIDSG11RNAPLHAPPS21EHYTIVFNTF31VLMQLFNEIN41ARKIHGERNV
51-10051FEGIFNNAIF61CTIVLGTFVV71QIIIVQFGGK81PFSCSELSIE91QWLWSIFLGM
101-150101GTLLWGQLIS111TIPTSRLKFL121KEAGHGTQKE131EIPEEELAED141VEEIDHAERE
151-200151LRRGQILWFR161GLNRIQTQMD171VVNAFQSGSS181IQGALRRQPS191IASQHHDIRV
201-250201VNAFRSSLYE211GLEKPESRSS221IHNFMTHPEF231RIEDSEPHIP241LIDDTDAEDD
251-300251APTKRNSSPP261PSPNKNNNAV271DSGIHLTIEM281NKSATSSSPG291SPLHSLETSL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 61 | - | - | - |
Deep-Palm: 0.13
|
|
| 84 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.41
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
4
PC3
Specificity: 0.333
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.333
4/4 (100.0%)
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
1
frontal cortex
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 162 | S → C | 0.004219 | SNP | Missense Mutation | SARC |
| 164 | V → Cfs*7 | 0.003460 | INS | Frame Shift Ins | CESC |
| 221 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 320 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 416 | F → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 697 | C → W | 0.003460 | SNP | Missense Mutation | CESC |
| 789 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 875 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |
| 1102 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 1102 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 1125 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |