Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A0U1RRM8 FERMT2 FERM domain containing kindlin 2 Homo sapiens (Human) 545 aa

Protein Details: A0A0U1RRM8 (FERMT2)

Protein Information
Accession A0A0U1RRM8
Protein Names FERM domain containing kindlin 2
Gene Symbol FERMT2
Organism Homo sapiens (Human)
Length 545 aa
Isoforms No isoforms
Related PMIDs 19801377 29575903 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.400
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.400
4/4 (100.0%)
1
DU145 cells
Specificity: 0.100
1/2 (50.0%)
1
HeLa cells
Specificity: 0.100
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MALELEGPLI11TPGSGTDVLY21IGPLKGSIYS31SPGLYSKTMT41PTYDAHDGSP
51-10051LSPTSAWFGD61SALSEGNPGI71LAVSQPITSP81EILAKMFKPQ91ALLDKAKINQ
101-150101GWLDSSRSLM111EQDVKENEAL121LLRFKYYSFF131DLNPKYDAIR141INQLYEQAKW
151-200151AILLEEIECT161EEEMMMFAAL171QYHINKLSIM181TSENHLNNSD191KEVDEVDAAL
201-250201SDLEITLEGG211KTSTILGDIT221SIPELADYIK231VFKPKKLTLK241GYKQYWCTFK
251-300251DTSISCYKSK261EESSGTPAHQ271MNLRGCEVTP281DVNISGQKFN291IKLLIPVAEG
301-350301MNEIWLRCDN311EKQYAHWMAA321CRLASKGKTM331ADSSYNLEVQ341NILSFLKMQH
351-400351LNPDPQLIPE361QITTDITPEC371LVSPRYLKKY381KNKQEKGCKK391HMPGYIRDLI
401-450401TARILEAHQN411VAQMSLIEAK421MRFIQAWQSL431PEFGITHFIA441RFQGGKKEEL
451-500451IGIAYNRLIR461MDASTGDAIK471TWRFSNMKQW481NVNWEIKMVT491VEFADEVRLS
501-545501FICTEVDCKV511VHEFIGGYIF521LSTRAKDQNE531SLDEEMFYKL541TSGWV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
276 CYSMODDB SWISSPALM DBPTM - -
321 Prediction (Medium) - -
370 Prediction (High) - -
388 Prediction (Medium) - -
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
115 F → C 0.007299 SNP Missense Mutation READ
397 C → C 0.006993 SNP Silent LAML
426 C → Mfs*2 0.002545 INS Frame Shift Ins GBM
439 F → C 0.002506 SNP Missense Mutation COAD
525 R → C 0.002747 SNP Missense Mutation LIHC
558 F → C 0.001887 SNP Missense Mutation UCEC
608 R → C 0.001887 SNP Missense Mutation UCEC
679 W → C 0.001764 SNP Missense Mutation LUAD