Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A1B0GUH5 | ASAH1 | Acid ceramidase (EC 3.5.1.23) (Acylsphingosine … | Homo sapiens (Human) | 393 aa |
Protein Details: A0A1B0GUH5 (ASAH1)
Protein Information
| Accession | A0A1B0GUH5 |
|---|---|
| Protein Names | Acid ceramidase (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (N-acylsphingosine amidohydrolase) |
| Gene Symbol | ASAH1 |
| Organism | Homo sapiens (Human) |
| Length | 393 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.929
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 0.929
26/46 (56.5%)
2
DU145 cells
Specificity: 0.071
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPGRSCVALV11LLAAAVSCAV21AQHAPPWTED31CRKSTYPPSG41PTYRGAVPWY
51-10051TINLDLPPYK61RWHELMLDKA71PVVIVNSLKN81MINTFVPSGK91IMQVVDEKLP
101-150101GLLGNFPGPF111EEEMKGIAAV121TDIPLGEIIS131FNIFYELFTI141CTSIVAEDKK
151-200151GHLIHGRNMD161FGVFLGWNIN171NDTWVITEQL181KPLTVNLDFQ191RNNKTVFKAS
201-250201SFAGYVGMLT211GFKPGLFSLT221LNERFSINGG231YLGILEWILG241KKDVMWIGFL
251-300251TRTVLENSTS261YEEAKNLLTK271TKILAPAYFI281LGGNQSGEGC291VITRDRKESL
301-350301DVYELDAKQG311RWYVVQTNYD321RWKHPFFLDD331RRTPAKMCLN341RTSQENISFE
351-393351TMYDVLSTKP361VLNKLTVYTT371LIDVTKGQFE381TYLRDCPDPC391IGW
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 6 | Prediction (High) | - | - |
| 18 | Prediction (Low) | - | - |
| 141 | Prediction (Medium) | - | - |
| 290 | Prediction (High) | - | - |
| 338 | Prediction (Medium) | - | - |
| 386 | Prediction (Low) | - | - |
| 390 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 314 | W → Cfs*28 | 0.002506 | DEL | Frame Shift Del | COAD |
| 384 | Y → C | 0.003460 | SNP | Missense Mutation | CESC |