Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A1B0GUW4 ASAH1 Acid ceramidase (EC 3.5.1.23) (Acylsphingosine … Homo sapiens (Human) 368 aa

Protein Details: A0A1B0GUW4 (ASAH1)

Protein Information
Accession A0A1B0GUW4
Protein Names Acid ceramidase (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (N-acylsphingosine amidohydrolase)
Gene Symbol ASAH1
Organism Homo sapiens (Human)
Length 368 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.929
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 0.929
26/46 (56.5%)
2
DU145 cells
Specificity: 0.071
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XLAAAVSCAV11AQHAPPVSEL21EPRRREGRAV31DRGLQKINLS41SFRTNLKVIV
51-10051NSLKNMINTF61VPSGKIMQVV71DEKLPGLLGN81FPGPFEEEMK91GIAAVTDIPL
101-150101GEIISFNIFY111ELFTICTSIV121AEDKKGHLIH131GRNMDFGVFL141GWNINNDTWV
151-200151ITEQLKPLTV161NLDFQRNNKT171VFKASSFAGY181VGMLTGFKPG191LFSLTLNERF
201-250201SINGGYLGIL211EWILGKKDVM221WIGFLTRTVL231ENSTSYEEAK241NLLTKTKILA
251-300251PAYFILGGNQ261SGEGCVITRD271RKESLDVYEL281DAKQGRWYVV291QTNYDRWKHP
301-350301FFLDDRRTPA311KMCLNRTSQE321NISFETMYDV331LSTKPVLNKL341TVYTTLIDVT
351-368351KGQFETYLRD361CPDPCIGW
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
8 Prediction (High) - -
116 Prediction (Medium) - -
265 Prediction (High) - -
313 Prediction (Medium) - -
361 Prediction (Low) - -
365 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
314 W → Cfs*28 0.002506 DEL Frame Shift Del COAD
384 Y → C 0.003460 SNP Missense Mutation CESC