Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A1B0GVG2 | ASAH1 | Acid ceramidase (EC 3.5.1.23) | Homo sapiens (Human) | 341 aa |
Protein Details: A0A1B0GVG2 (ASAH1)
Protein Information
| Accession | A0A1B0GVG2 |
|---|---|
| Protein Names | Acid ceramidase (EC 3.5.1.23) |
| Gene Symbol | ASAH1 |
| Organism | Homo sapiens (Human) |
| Length | 341 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.929
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 0.929
26/46 (56.5%)
2
DU145 cells
Specificity: 0.071
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNCCIGLGEK11ARGSHRASYP21SLSALFTEAS31ILGFGSFAVK41AQWTEDCRKS
51-10051TYPPSGPTYR61GAVPWYTINL71DLPPYKRWHE81LMLDKAPVLK91VIVNSLKNMI
101-150101NTFVPSGKIM111QVVDEKLPGL121LGNFPGPFEE131EMKGIAAVTD141IPLGEIISFN
151-200151IFYELFTICT161SIVAEDKKGH171LIHGRNMDFG181VFLGWNINND191TWVITEQLKP
201-250201LTVNLDFQRN211NKTVFKASSF221AGYVGMLTGF231KPGLFSLTLN241ERFSINGGYL
251-300251GILEWILGKK261DVMWIGFLTR271TVLENSTSYE281EAKNLLTKTK291ILAPAYFILG
301-341301GNQSGEGCVI311TRDRKESLDV321YEISHLKPCM331MSCQQNLSST341S
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 3 | Prediction (High) | - | - |
| 4 | Prediction (High) | - | - |
| 159 | Prediction (Medium) | - | - |
| 308 | Prediction (High) | - | - |
| 333 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 314 | W → Cfs*28 | 0.002506 | DEL | Frame Shift Del | COAD |
| 384 | Y → C | 0.003460 | SNP | Missense Mutation | CESC |