Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A1B0GW68 ASAH1 Acid ceramidase (EC 3.5.1.23) (Acylsphingosine … Homo sapiens (Human) 374 aa

Protein Details: A0A1B0GW68 (ASAH1)

Protein Information
Accession A0A1B0GW68
Protein Names Acid ceramidase (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (N-acylsphingosine amidohydrolase)
Gene Symbol ASAH1
Organism Homo sapiens (Human)
Length 374 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.929
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 0.929
26/46 (56.5%)
2
DU145 cells
Specificity: 0.071
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPGRSCVALV11LLAAAVSCAV21AQHAPPWTED31CRKSTYPPSG41PTYRGAVPWY
51-10051TINLDLPPYK61RWHELMLDKA71PVLKVIVNSL81KNMINTFVPS91GKIMQVVDEK
101-150101LPGLLGNFPG111PFEEEMKGIA121AVTDIPLEDK131KGHLIHGRNM141DFGVFLGWNI
151-200151NNDTWVITEQ161LKPLTVNLDF171QRNNKTVFKA181SSFAGYVGML191TGFKPGLFSL
201-250201TLNERFSING211GYLGILEWIL221GKKDVMWIGF231LTRTVLENST241SYEEAKNLLT
251-300251KTKILAPAYF261ILGGNQSGEG271CVITRDRKES281LDVYELDAKQ291GRWYVVQTNY
301-350301DRWKHPFFLD311DRRTPAKMCL321NRTSQENISF331ETMYDVLSTK341PVLNKLTVYT
351-374351TLIDVTKGQF361ETYLRDCPDP371CIGW
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
6 Prediction (High) - -
18 Prediction (Low) - -
271 Prediction (High) - -
319 Prediction (Medium) - -
367 Prediction (Low) - -
371 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
314 W → Cfs*28 0.002506 DEL Frame Shift Del COAD
384 Y → C 0.003460 SNP Missense Mutation CESC