Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A1C7CYX9 | DPYSL2 | Dihydropyrimidinase-related protein 2 | Homo sapiens (Human) | 677 aa |
Protein Details: A0A1C7CYX9 (DPYSL2)
Protein Information
| Accession | A0A1C7CYX9 |
|---|---|
| Protein Names | Dihydropyrimidinase-related protein 2 |
| Gene Symbol | DPYSL2 |
| Organism | Homo sapiens (Human) |
| Length | 677 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 0.500
4/4 (100.0%)
3
PC3 cells
Specificity: 0.375
3/4 (75.0%)
1
Endothelial cells
Specificity: 0.125
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAERKQSGKA11AEDEEVPAFF21KNLGSGSPKP31RQKFCGMFCP41VEGSSENKTI
51-10051DFDSLSVGRG61SGQVVAQQRD71VAHLGPDPQP81PYSRQGRRAG91GEPSVESGRK
101-150101VEIRRASGKE111ALQNINDQSD121RLLIKGGKIV131NDDQSFYADI141YMEDGLIKQI
151-200151GENLIVPGGV161KTIEAHSRMV171IPGGIDVHTR181FQMPDQGMTS191ADDFFQGTKA
201-250201ALAGGTTMII211DHVVPEPGTS221LLAAFDQWRE231WADSKSCCDY241SLHVDISEWH
251-300251KGIQEEMEAL261VKDHGVNSFL271VYMAFKDRFQ281LTDCQIYEVL291SVIRDIGAIA
301-350301QVHAENGDII311AEEQQRILDL321GITGPEGHVL331SRPEEVEAEA341VNRAITIANQ
351-400351TNCPLYITKV361MSKSSAEVIA371QARKKGTVVY381GEPITASLGT391DGSHYWSKNW
401-450401AKAAAFVTSP411PLSPDPTTPD421FLNSLLSCGD431LQVTGSAHCT441FNTAQKAVGK
451-500451DNFTLIPEGT461NGTEERMSVI471WDKAVVTGKM481DENQFVAVTS491TNAAKVFNLY
501-550501PRKGRIAVGS511DADLVIWDPD521SVKTISAKTH531NSSLEYNIFE541GMECRGSPLV
551-600551VISQGKIVLE561DGTLHVTEGS571GRYIPRKPFP581DFVYKRIKAR591SRLAELRGVP
601-650601RGLYDGPVCE611VSVTPKTVTP621ASSAKTSPAK631QQAPPVRNLH641QSGFSLSGAQ
651-677651IDDNIPRRTT661QRIVAPPGGR671ANITSLG
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 39 | Prediction (Medium) | - | - |
| 353 | Prediction (High) | - | - |
| 544 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 75 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 75 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 173 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 179 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 238 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 238 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 248 | C → Y | 0.002545 | SNP | Missense Mutation | GBM |
| 334 | C → S | 0.002545 | SNP | Missense Mutation | GBM |
| 400 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 440 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 467 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 572 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |