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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A1Y1BBN3 DHCR7 7-dehydrocholesterol reductase (7-DHC) (Delta-14-SR) (EC … Homo sapiens (Human) 198 aa

Protein Details: A0A1Y1BBN3 (DHCR7)

Protein Information
Accession A0A1Y1BBN3
Protein Names 7-dehydrocholesterol reductase (7-DHC) (Delta-14-SR) (EC 1.3.1.21) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (Delta(14)-sterol reductase TM7SF2) (Sterol C14-reductase) (Sterol Delta(7)-reductase) (Transmembrane 7 superfamily member 2)
Gene Symbol DHCR7
Organism Homo sapiens (Human)
Length 198 aa
Isoforms No isoforms
Related PMIDs 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Cerebral cortex
Specificity: 1.000
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501AIYVIDFFWN11ETWYLKTIDI21CHDHFXWYLG31WGDCVWLPYL41YTLQGLYLVY
51-10051HPVQLSTPHA61VGVLLLGLVG71YYIFRVANHQ81KDLFRRTDGR91CLIWGRKPKV
101-150101IECSYTSADG111QRHHSKLLVS121GFWGVARHFN131YVGDLMGSLA141YCLACGGGHL
151-198151LPYFYIIYMA161ILLTHRCLRD171EHRCASKYGR181DWERYTAAVP191YRLLPGIF
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
91 Prediction (Low) - -
103 Prediction (Medium) - -
167 Prediction (Medium) - -
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
209 C → S 0.001764 SNP Missense Mutation LUAD
242 R → C 0.002288 SNP Missense Mutation STAD
367 R → C 0.002506 SNP Missense Mutation COAD
380 C → C 0.001887 SNP Silent UCEC
381 S → C 0.002427 SNP Missense Mutation BLCA
425 G → C 0.004219 SNP Missense Mutation SARC
451 C → C 0.005618 SNP Silent PAAD
462 Y → C 0.002288 SNP Missense Mutation STAD