Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A2R8Y2A8 | AP3B2 | AP-3 complex subunit beta | Homo sapiens (Human) | 1125 aa |
Protein Details: A0A2R8Y2A8 (AP3B2)
Protein Information
| Accession | A0A2R8Y2A8 |
|---|---|
| Protein Names | AP-3 complex subunit beta |
| Gene Symbol | AP3B2 |
| Organism | Homo sapiens (Human) |
| Length | 1125 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
1
Prefrontal cortex
Specificity: 1.000
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MQRFLQLPGA11VVRPGVRGAC21GADQEAASPV31LAPEGGPPLR41YQALEPEELR
51-10051WLQAQEEDTT61PEASLEGPCP71EASQSQSQPL81RHDDLKEMLD91TNKDSLKLEA
101-150101MKRIVAMIAR111GKNASDLFPA121VVKNVACKNI131EVKKLVYVYL141VRYAEEQQDL
151-200151ALLSISTFQR161GLKDPNQLIR171ASALRVLSSI181RVPIIVPIMM191LAIKEAASDM
201-250201SPYVRKTAAH211AIPKLYSLDS221DQKDQLIEVI231EKLLADKTTL241VAGSVVMAFE
251-300251EVCPERIDLI261HKNYRKLCNL271LIDVEEWGQV281VIISMLTRYA291RTQFLSPTQN
301-350301ESLLEENAEK311AFYGSEEDEA321KGAGSEETAA331AAAPSRKPYV341MDPDHRLLLR
351-400351NTKPLLQSRS361AAVVMAVAQL371YFHLAPKAEV381GVIAKALVRL391LRSHSEVQYV
401-450401VLQNVATMSI411KRRGMFEPYL421KSFYIRSTDP431TQIKILKLEV441LTNLANETNI
451-500451PTVLREFQTY461IRSMDKDFVA471ATIQAIGRCA481TNIGRVRDTC491LNGLVQLLSN
501-550501RDELVVAESV511VVIKKLLQMQ521PAQHGEIIKH531LAKLTDNIQV541PMARASILWL
551-600551IGEYCEHVPR561IAPDVLRKMA571KSFTAEEDIV581KLQVINLAAK591LYLTNSKQTK
601-650601LLTQYVLSLA611KYDQNYDIRD621RARFTRQLIV631PSEQGGALSR641HAKKLFLAPK
651-700651PAPVLESSFK661DRDHFQLGSL671SHLLNAKATG681YQELPDWPEE691APDPSVRNVE
701-750701VPEWTKCSNR711EKRKEKEKPF721YSDSEGESGP731TESADSDPES741ESESDSKSSS
751-800751ESGSGESSSE761SDNEDQDEDE771EKGRGSESEQ781SEEDGKRKTK791KKVPERKGEA
801-850801SSSDEGSDSS811SSSSESEMTS821ESEEEQLEPA831SWSRKTPPSS841KSAPATKEIS
851-900851LLDLEDFTPP861SVQPVSPPAI871VSTSLAADLE881GLTLTDSTLV891PSLLSPVSGV
901-950901GRQELLHRVA911GEGLAVDYTF921SRQPFSGDPH931MVSVHIHFSN941SSDTPIKGLH
951-1000951VGTPKLPAGI961SIQEFPEIES971LAPGESATAV981MGINFCDSTQ991AANFQLCTQT
1001-10501001RQFYVSIQPP1011VGELMAPVFM1021SENEFKKEQG1031KLMGMNEITE1041KLMLPDTCRS
1051-11001051DHIVVQKVTA1061TANLGRVPCG1071TSDEYRFAGR1081TLTGGSLVLL1091TLDARPAGAA
1101-11251101QLTVNSEKMV1111IGTMLVKDVI1121QALTQ
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 20 | Prediction (Medium) | - | - |
| 127 | Prediction (Medium) | - | - |
| 253 | Prediction (Medium) | - | - |
| 268 | Prediction (Low) | - | - |
| 479 | Prediction (High) | - | - |
| 490 | Prediction (Medium) | - | - |
| 1048 | Prediction (Medium) | - | - |
| 1069 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 100 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 127 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 127 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 132 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 435 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 444 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 444 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 576 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 580 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 654 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 654 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 707 | S → C | 0.002506 | SNP | Missense Mutation | COAD |
| 710 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 844 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 954 | C → C | 0.002294 | SNP | Splice Region | OV |
| 1026 | C → Y | 0.002747 | SNP | Missense Mutation | LIHC |