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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A2R8Y535 ATP2B2 ATPase plasma membrane Ca2+ transporting … Homo sapiens (Human) 387 aa

Protein Details: A0A2R8Y535 (ATP2B2)

Protein Information
AccessionA0A2R8Y535
Protein NamesATPase plasma membrane Ca2+ transporting 2
Gene SymbolATP2B2
OrganismHomo sapiens (Human)
Length387 aa
IsoformsNo isoforms
Related PMIDs 26876311
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501GPALKKADVG11FAMGIAGTDV21AKEASDIILT31DDNFSSIVKA41VMWGRNVYDS
51-10051ISKFLQFQLT61VNVVAVIVAF71TGACITQDSP81LKAVQMLWVN91LIMDTFASLA
101-150101LATEPPTETL111LLRKPYGRNK121PLISRTMMKN131ILGHAVYQLA141LIFTLLFVGE
151-200151KMFQIDSGRN161APLHSPPSEH171YTIIFNTFVM181MQLFNEINAR191KIHGERNVFD
201-250201GIFRNPIFCT211IVLGTFAIQI221VIVQFGGKPF231SCSPLQLDQW241MWCIFIGLGE
251-300251LVWGQSRIGC261LQGPVTSGGI271RDRGISNPRR281TEGQPRARLM291QDELDPPPCP
301-350301VLTMPRAAPT311LQLGKPKLGH321RHHPDQQTQV331PQGGRQAHTE341GGDPGGGAQR
351-387351GRGGDRPRGA361GAAAGPDPVV371PRPESDPDTD381PRREGVP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
74 - - -
GPS-Palm: 0.86
Deep-Palm: 0.92
209 - - -
Deep-Palm: 0.38
232 - - -
GPS-Palm: 0.88
Deep-Palm: 0.08
243 - - -
Deep-Palm: 0.10
260 - - -
GPS-Palm: 0.76
Deep-Palm: 0.94
299 - - -
Deep-Palm: 0.82
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
frontal cortex
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
32 R → C 0.002141 SNP Missense Mutation SKCM
32 R → C 0.001887 SNP Missense Mutation UCEC
59 R → C 0.002294 SNP Missense Mutation OV
86 F → C 0.007299 SNP Missense Mutation READ
151 W → C 0.001887 SNP Missense Mutation UCEC
185 R → C 0.001764 SNP Missense Mutation LUAD
249 R → C 0.002288 SNP Missense Mutation STAD
249 R → C 0.002506 SNP Missense Mutation COAD
432 C → S 0.006944 SNP Missense Mutation TGCT
491 G → C 0.002033 SNP Missense Mutation LUSC
497 C → S 0.001764 SNP Missense Mutation LUAD
559 G → C 0.002288 SNP Missense Mutation STAD
588 R → C 0.001887 SNP Missense Mutation UCEC
597 Y → C 0.001887 SNP Missense Mutation UCEC
606 R → C 0.001969 SNP Missense Mutation HNSC
606 R → C 0.002020 SNP Missense Mutation PRAD
606 R → C 0.001887 SNP Missense Mutation UCEC
621 R → C 0.001764 SNP Missense Mutation LUAD
621 R → C 0.002141 SNP Missense Mutation SKCM
651 R → C 0.001887 SNP Missense Mutation UCEC
666 C → C 0.001887 SNP Silent UCEC
673 C → C 0.001887 SNP Silent UCEC
677 R → C 0.005435 SNP Missense Mutation ESCA
699 C → C 0.001887 SNP Silent UCEC
869 R → C 0.001887 SNP Missense Mutation UCEC
1014 R → C 0.001887 SNP Missense Mutation UCEC
1020 R → C 0.001887 SNP Missense Mutation UCEC
1055 S → C 0.002747 SNP Missense Mutation LIHC
1067 C → C 0.003460 SNP Silent CESC
1142 R → C 0.002141 SNP Missense Mutation SKCM
1178 S → C 0.002294 SNP Missense Mutation OV
1211 S → C 0.001764 SNP Missense Mutation LUAD