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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A3B3ISQ1 ADAM17 ADAM metallopeptidase domain 17 Homo sapiens (Human) 181 aa

Protein Details: A0A3B3ISQ1 (ADAM17)

Protein Information
Accession A0A3B3ISQ1
Protein Names ADAM metallopeptidase domain 17
Gene Symbol ADAM17
Organism Homo sapiens (Human)
Length 181 aa
Isoforms No isoforms
Related PMIDs 19801377
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
2
DU145 cells
Specificity: 1.000
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLSDYDILSL11SNIQQHSVRK21RDLQTSTHVE31TLLTFSALKR41HFKLYLTSST
51-10051ERFSQNFKVV61VVDGKNESEY71TVKWQDFFTG81HVVGEPDSRV91LAHIRDDDVI
101-150101IRINTDGAEY111NIERWGFTVL121VRLFSNSWTQ131VICPPWPPQS141AEITGVSHRA
151-181151RQFSYIDGVV161QTPPHSILEH171FYHLKKKRCI181L
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
179 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
177 R → C 0.002506 SNP Missense Mutation COAD
283 R → C 0.002545 SNP Missense Mutation GBM
330 S → C 0.002506 SNP Missense Mutation COAD
519 S → C 0.001969 SNP Missense Mutation HNSC
630 C → C 0.001887 SNP Silent UCEC
641 C → C 0.001014 SNP Silent BRCA
641 C → Y 0.001887 SNP Missense Mutation UCEC
785 S → C 0.002545 SNP Missense Mutation GBM
786 S → C 0.002294 SNP Missense Mutation OV
813 R → C 0.001014 SNP Missense Mutation BRCA
813 R → C 0.001969 SNP Missense Mutation HNSC
824 C → C 0.001887 SNP Silent UCEC