Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A3B3ISY9 | AGK | Acylglycerol kinase, mitochondrial (EC 2.7.1.107) … | Homo sapiens (Human) | 330 aa |
Protein Details: A0A3B3ISY9 (AGK)
Protein Information
| Accession | A0A3B3ISY9 |
|---|---|
| Protein Names | Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) |
| Gene Symbol | AGK |
| Organism | Homo sapiens (Human) |
| Length | 330 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDVTIVKTDY11EGQAKKLLEL21MENTDVIIVA31GGDGTLQEVV41TGVLRRTDEA
51-10051TFSKIPIGFI61PLGETSSLSH71TLFAESGNKV81QHITDATLAI91VKGETVPLDV
101-150101LQIKGEKEQP111VFAMTGLRWG121SFRDAGVKVS131KYWYLGPLKI141KAAHFFSTLK
151-200151EWPQTHQASI161SYTGPTERPP171NEPEETPVQR181PSLYRRILRR191LASYWAQPQD
201-250201ALSQEVSPEV211WKDVQLSTIE221LSITTRNNQL231DPTSKEDFLN241ICIEPDTISK
251-300251GDFITIGSRK261VRNPKLHVEG271TECLQASQCT281LLIPEGAGGS291FSIDSEEYEA
301-330301MPVEVKLLPR311KLQFFCDPRK321REQMLTSPTQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 242 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.50
|
|
| 273 | - | - | - |
Deep-Palm: 0.95
|
|
| 279 | - | - | - |
Deep-Palm: 0.95
|
|
| 316 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
PC3
Specificity: 0.500
2/2 (100.0%)
1
frontal cortex
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.250
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 197 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 224 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 244 | W → C | 0.004219 | SNP | Missense Mutation | SARC |
| 365 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |