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UniProt ID Gene Symbol Protein Name Organism Length Action
A0A590UJE5 AP3B2 Adaptor related protein complex 3 … Homo sapiens (Human) 718 aa

Protein Details: A0A590UJE5 (AP3B2)

Protein Information
AccessionA0A590UJE5
Protein NamesAdaptor related protein complex 3 subunit beta 2
Gene SymbolAP3B2
OrganismHomo sapiens (Human)
Length718 aa
IsoformsNo isoforms
Related PMIDs 26876311
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSIKRRGMFE11PYLKSFYIRS21TDPTQIKILK31LEVLTNLANE41TNIPTVLREF
51-10051QTYIRSMDKD61FVAATIQAIG71RCATNIGRVR81DTCLNGLVQL91LSNRDELVVA
101-150101ESVVVIKKLL111QMQPAQHGEI121IKHLAKLTDN131IQVPMARASI141LWLIGEYCEH
151-200151VPRIAPDVLR161KMAKSFTAEE171DIVKLQVINL181AAKLYLTNSK191QTKLLTQYVL
201-250201SLAKYDQNYD211IRDRARFTRQ221LIVPSEQGGA231LSRHAKKLFL241APKPAPVLES
251-300251SFKDRDHFQL261GSLSHLLNAK271ATGYQELPDW281PEEAPDPSVR291NVEVPEWTKC
301-350301SNREKRKEKE311KPFYSDSEGE321SGPTESADSD331PESESESDSK341SSSESGSGES
351-400351SSESDNEDQD361EDEEKGRGSE371SEQSEEDGKR381KTKKKVPERK391GEASSSDEGS
401-450401DSSSSSSESE411MTSESEEEQL421EPASWSRKTP431PSSKSAPATK441EISLLDLEDF
451-500451TPPSVQPVSP461PAIVSTSLAA471DLEGLTLTDS481TLVPSLLSPV491SGVGRQELLH
501-550501RVAGEGLAVD511YTFSRQPFSG521DPHMVSVHIH531FSNSSDTPIK541GLHVGTPKLP
551-600551AGISIQEFPE561IESLAPGESA571TAVMGINFCD581STQAANFQLC591TQTRQFYVSI
601-650601QPPVGELMAP611VFMSENEFKK621EQGKLMGMNE631ITEKLMLPDT641CRSDHIVVQK
651-700651VTATANLGRV661PCGTSDEYRF671AGRTLTGGSL681VLLTLDARPA691GAAQLTVNSE
701-718701KMVIGTMLVK711DVIQALTQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
72 - - -
GPS-Palm: 0.90
Deep-Palm: 0.76
83 - - -
GPS-Palm: 0.88
Deep-Palm: 0.85
148 - - -
Deep-Palm: 0.93
300 - - -
Deep-Palm: 0.91
579 - - -
Deep-Palm: 0.50
590 - - -
Deep-Palm: 0.10
641 - - -
GPS-Palm: 0.80
Deep-Palm: 0.42
662 - - -
GPS-Palm: 0.67
Deep-Palm: 0.92
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
frontal cortex
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
100 Y → C 0.002747 SNP Missense Mutation LIHC
127 R → C 0.002506 SNP Missense Mutation COAD
127 R → C 0.004283 SNP Missense Mutation SKCM
132 R → C 0.002288 SNP Missense Mutation STAD
435 R → C 0.007299 SNP Missense Mutation READ
444 R → C 0.002506 SNP Missense Mutation COAD
444 R → C 0.002141 SNP Missense Mutation SKCM
576 R → C 0.003774 SNP Missense Mutation UCEC
580 R → C 0.002506 SNP Missense Mutation COAD
654 R → C 0.002427 SNP Missense Mutation BLCA
654 R → C 0.001887 SNP Missense Mutation UCEC
707 S → C 0.002506 SNP Missense Mutation COAD
710 G → C 0.001764 SNP Missense Mutation LUAD
844 S → C 0.002427 SNP Missense Mutation BLCA
954 C → C 0.002294 SNP Splice Region OV
1026 C → Y 0.002747 SNP Missense Mutation LIHC