Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A590UK04 | AP3B2 | AP-3 complex subunit beta | Homo sapiens (Human) | 1025 aa |
Protein Details: A0A590UK04 (AP3B2)
Protein Information
| Accession | A0A590UK04 |
|---|---|
| Protein Names | AP-3 complex subunit beta |
| Gene Symbol | AP3B2 |
| Organism | Homo sapiens (Human) |
| Length | 1025 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSAAPAYSED11KGGSAGPGEP21EYGHDPASGG31IFSSDYKRHD41DLKEMLDTNK
51-10051DSLKLEAMKR61IVADPNQLIR71ASALRVLSSI81RVPIIVPIMM91LAIKEAASDM
101-150101SPYVRKTAAH111AIPKLYSLDS121DQKDQLIEVI131EKLLADKTTL141VAGSVVMAFE
151-200151EVCPERIDLI161HKNYRKLCNL171LIDVEEWGQV181VIISMLTRYA191RTQFLSPTQN
201-250201ESLLEENAEK211AFYGSEEDEA221KGAGSEETAA231AAAPSRKPYV241MDPDHRLLLR
251-300251NTKPLLQSRS261AAVVMAVAQL271YFHLAPKAEV281GVIAKALVRL291LRSHSEVQYV
301-350301VLQNVATMSI311KRRGMFEPYL321KSFYIRSTDP331TQIKILKLEV341LTNLANETNI
351-400351PTVLREFQTY361IRSMDKDFVA371ATIQAIGRCA381TNIGRVRDTC391LNGLVQLLSN
401-450401RDELVVAESV411VVIKKLLQMQ421PAQHGEIIKH431LAKLTDNIQV441PMARASILWL
451-500451IGEYCEHVPR461IAPDVLRKMA471KSFTAEEDIV481KLQVINLAAK491LYLTNSKQTK
501-550501LLTQYVLSLA511KYDQNYDIRD521RARFTRQLIV531PSEQGGALSR541HAKKLFLAPK
551-600551PAPVLESSFK561DRDHFQLGSL571SHLLNAKATG581YQELPDWPEE591APDPSVRNVE
601-650601VPEWTKCSNR611EKRKEKEKPF621YSDSEGESGP631TESADSDPES641ESESDSKSSS
651-700651ESGSGESSSE661SDNEDQDEDE671EKGRGSESEQ681SEEDGKRKTK691KKVPERKGEA
701-750701SSSDEGSDSS711SSSSESEMTS721ESEEEQLEPA731SWSRKTPPSS741KSAPATKEIS
751-800751LLDLEDFTPP761SVQPVSPPAI771VSTSLAADLE781GLTLTDSTLV791PSLLSPVSGV
801-850801GRQELLHRVA811GEGLAVDYTF821SRQPFSGDPH831MVSVHIHFSN841SSDTPIKGLH
851-900851VGTPKLPAGI861SIQEFPEIES871LAPGESATAV881MGINFCDSTQ891AANFQLCTQT
901-950901RQFYVSIQPP911VGELMAPVFM921SENEFKKEQG931KLMGMNEITE941KLMLPDTCRS
951-1000951DHIVVQKVTA961TANLGRVPCG971TSDEYRFAGR981TLTGGSLVLL991TLDARPAGAA
1001-10251001QLTVNSEKMV1011IGTMLVKDVI1021QALTQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 153 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.74
|
|
| 168 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.72
|
|
| 379 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.76
|
|
| 390 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.85
|
|
| 455 | - | - | - |
Deep-Palm: 0.93
|
|
| 607 | - | - | - |
Deep-Palm: 0.91
|
|
| 886 | - | - | - |
Deep-Palm: 0.50
|
|
| 897 | - | - | - |
Deep-Palm: 0.10
|
|
| 948 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.42
|
|
| 969 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.92
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
frontal cortex
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 100 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 127 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 127 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 132 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 435 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 444 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 444 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 576 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 580 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 654 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 654 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 707 | S → C | 0.002506 | SNP | Missense Mutation | COAD |
| 710 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 844 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 954 | C → C | 0.002294 | SNP | Splice Region | OV |
| 1026 | C → Y | 0.002747 | SNP | Missense Mutation | LIHC |