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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A590UKD3 AP3B2 AP complex subunit beta Homo sapiens (Human) 528 aa

Protein Details: A0A590UKD3 (AP3B2)

Protein Information
AccessionA0A590UKD3
Protein NamesAP complex subunit beta
Gene SymbolAP3B2
OrganismHomo sapiens (Human)
Length528 aa
IsoformsNo isoforms
Related PMIDs 26876311
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSAAPAYSED11KGGSAGPGEP21EYGHDPASGG31IFSSDYKRHD41DLKEMLDTNK
51-10051DSLKLEAMKR61IVAMIARGKN71ASDLFPAVVK81NVACKNIEDP91NQLIRASALR
101-150101VLSSIRVPII111VPIMMLAIKE121AASDMSPYVR131KTAAHAIPKL141YSLDSDQKDQ
151-200151LIEVIEKLLA161DKTTLVAGSV171VMAFEEVCPE181RIDLIHKNYR191KLCNLLIDVE
201-250201EWGQVVIISM211LTRYARTQFL221SPTQNESLLE231ENAEKAFYGS241EEDEAKGAGS
251-300251EETAAAAAPS261RKPYVMDPDH271RLLLRNTKPL281LQSRSAAVVM291AVAQLYFHLA
301-350301PKAEVGVIAK311ALVRLLRSHS321EVQYVVLQNV331ATMSIKRRGM341FEPYLKSFYI
351-400351RSTDPTQIKI361LKLEVLTNLA371NETNIPTVLR381EFQTYIRSMD391KDFVAATIQA
401-450401IGRCATNIGR411VRDTCLNGLV421QLLSNRDELV431VAESVVVIKK441LLQMQPAQHG
451-500451EIIKHLAKLT461DNIQVPMARA471SILWLIGEYC481EHVPRIAPDV491LRKMAKSFTA
501-528501EEDIVKLQVI511NLAAKLYLTN521SKQVKIKR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
84 - - -
GPS-Palm: 0.66
Deep-Palm: 0.95
178 - - -
GPS-Palm: 0.87
Deep-Palm: 0.74
193 - - -
GPS-Palm: 0.68
Deep-Palm: 0.72
404 - - -
GPS-Palm: 0.90
Deep-Palm: 0.76
415 - - -
GPS-Palm: 0.88
Deep-Palm: 0.85
480 - - -
Deep-Palm: 0.93
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
frontal cortex
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
100 Y → C 0.002747 SNP Missense Mutation LIHC
127 R → C 0.002506 SNP Missense Mutation COAD
127 R → C 0.004283 SNP Missense Mutation SKCM
132 R → C 0.002288 SNP Missense Mutation STAD
435 R → C 0.007299 SNP Missense Mutation READ
444 R → C 0.002506 SNP Missense Mutation COAD
444 R → C 0.002141 SNP Missense Mutation SKCM
576 R → C 0.003774 SNP Missense Mutation UCEC
580 R → C 0.002506 SNP Missense Mutation COAD
654 R → C 0.002427 SNP Missense Mutation BLCA
654 R → C 0.001887 SNP Missense Mutation UCEC
707 S → C 0.002506 SNP Missense Mutation COAD
710 G → C 0.001764 SNP Missense Mutation LUAD
844 S → C 0.002427 SNP Missense Mutation BLCA
954 C → C 0.002294 SNP Splice Region OV
1026 C → Y 0.002747 SNP Missense Mutation LIHC