Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A7I2V3Z0 | PFKP | ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC … | Homo sapiens (Human) | 746 aa |
Protein Details: A0A7I2V3Z0 (PFKP)
Protein Information
| Accession | A0A7I2V3Z0 |
|---|---|
| Protein Names | ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase) |
| Gene Symbol | PFKP |
| Organism | Homo sapiens (Human) |
| Length | 746 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
5
Jurkat T cells
Specificity: 0.625
5/25 (20.0%)
3
PC3 cells
Specificity: 0.375
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNAAVRAVVR11MGIYVGAKVY21FIYEGYQGMV31DGGSNIAEAD41WESVSSILQV
51-10051GGTIIGSARC61QAFRTREGRL71KAACNLLQRG81ITNLCVIGGD91GSLTGANLFR
101-150101KEWSGLLEEL111ARNGQIDKEA121VQKYAYLNVV131GMVGSIDNDF141CGTDMTIGTD
151-200151SALHRIIEVV161DAIMTTAQSH171QRTFVLEVMG181RHCGYLALVS191ALACGADWVF
201-250201LPESPPEEGW211EEQMCVKLSE221NRARKKRLNI231IIVAEGAIDT241QNKPITSEKI
251-300251KELVVTQLGY261DTRVTILGHV271QRGGTPSAFD281RILASRMGVE291AVIALLEATP
301-350301DTPACVVSLN311GNHAVRLPLM321ECVQMTQDVQ331KAMDERRFQD341AVRLRGRSFA
351-400351GNLNTYKRLA361IKLPDDQIPK371TNCNVAVINV381GAPAAGMNAA391VRSAVRVGIA
401-450401DGHRMLAIYD411GFDGFAKGQI421KEIGWTDVGG431WTGQGGSILG441TKRVLPGKYL
451-500451EEIATQMRTH461SINALLIIGG471FEAYLGLLEL481SAAREKHEEF491CVPMVMVPAT
501-550501VSNNVPGSDF511SIGADTALNT521ITDTCDRIKQ531SASGTKRRVF541IIETMGGYCG
551-600551YLANMGGLAA561GADAAYIFEE571PFDIRDLQSN581VEHLTEKMKT591TIQRGLVLRN
601-650601ESCSENYTTD611FIYQLYSEEG621KGVFDCRKNV631LGHMQQGGAP641SPFDRNFGTK
651-700651ISARAMEWIT661AKLKEARGRG671KKFTTDDSIC681VLGISKRNVI691FQPVAELKKQ
701-746701TDFEHRIPKE711QWWLKLRPLM721KILAKYKASY731DVSDSGQLEH741VQPWSV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 60 | Prediction (Medium) | - | - |
| 74 | Prediction (High) | - | - |
| 85 | Prediction (Medium) | - | - |
| 141 | Prediction (Low) | - | - |
| 183 | Prediction (Low) | - | - |
| 322 | Prediction (Medium) | - | - |
| 525 | Prediction (Medium) | - | - |
| 549 | Prediction (Low) | - | - |
| 603 | Prediction (Low) | - | - |
| 680 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 44 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 44 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 48 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 48 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 48 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 117 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 118 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 343 | C → C | 0.004577 | SNP | Silent | STAD |
| 354 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 354 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 440 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 563 | C → C | 0.001887 | SNP | Silent | UCEC |
| 576 | R → C | 0.002288 | SNP | Missense Mutation | STAD |