Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A7P0T8S7 | OAS3 | 2'-5'-oligoadenylate synthase 3 (EC 2.7.7.84) | Homo sapiens (Human) | 1036 aa |
Protein Details: A0A7P0T8S7 (OAS3)
Protein Information
| Accession | A0A7P0T8S7 |
|---|---|
| Protein Names | 2'-5'-oligoadenylate synthase 3 (EC 2.7.7.84) |
| Gene Symbol | OAS3 |
| Organism | Homo sapiens (Human) |
| Length | 1036 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
2
PC3 cells
Specificity: 1.000
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDLYSTPAAA11LDRFVARRLQ21PRKEFVEKAR31RALGALAAAL41RERGGRLGAA
51-10051APRVLKTVKG61GSSGRGTALK71GGCDSELVIF81LDCFKSYVDQ91RARRAEILSE
101-150101MRASLESWWQ111NPVPGLRLTF121PEQSVPGALQ131FRLTSVDLED141WMDVSLVPAF
151-200151NVLGQAGSGV161KPKPQVYSTL171LNSGCQGGEH181AACFTELRRN191FVNIRPAKLK
201-250201NLILLVKHWY211HQVCLQGLWK221ETLPPVYALE231LLTIFAWEQG241CKKDAFSLAE
251-300251GLRTVLGLIQ261QHQHLCVFWT271VNYGFEDPAV281GQFLQRQLKR291PRPVILDPAD
301-350301PTWDLGNGAA311WHWDLLAQEA321ASCYDHPCFL331RGMGDPVQSW341KGPGLPRAGC
351-400351SGLGHPIQLD361PNQKTPENSK371SLNAVYPRAG381SKPPSCPAPG391PTGAASIVPS
401-450401VPGMALDLSQ411IPTKELDRFI421QDHLKPSPQF431QEQVKKAIDI441ILRCLHENCV
451-500451HKASRVSKGG461SFGRGTDLRD471GCDVELIIFL481NCFTDYKDQG491PRRAEILDEM
501-550501RAQLESWWQD511QVPSLSLQFP521EQNVPEALQF531QLVSTALKSW541TDVSLLPAFD
551-600551AVGQLSSGTK561PNPQVYSRLL571TSGCQEGEHK581ACFAELRRNF591MNIRPVKLKN
601-650601LILLVKHWYR611QVAAQNKGKG621PAPASLPPAY631ALELLTIFAW641EQGCRQDCFN
651-700651MAQGFRTVLG661LVQQHQQLCV671YWTVNYSTED681PAMRMHLLGQ691LRKPRPLVLD
701-750701PADPTWNVGH711GSWELLAQEA721AALGMQACFL731SRDGTSVQPW741DVMPALLYQT
751-800751PAGDLDKFIS761EFLQPNRQFL771AQVNKAVDTI781CSFLKENCFR791NSPIKVIKVV
801-850801KERQFEVKFE811VSKWENPRVL821SFSLTSQTML831DQSVDFDVLP841AFDALGQLVS
851-900851GSRPSSQVYV861DLIHSYSNAG871EYSTCFTELQ881RDFIISRPTK891LKSLIRLVKH
901-950901WYQQCTKISK911GRGSLPPQHG921LELLTVYAWE931QGGKDSQFNM941AEGFRTVLEL
951-1000951VTQYRQLCIY961WTINYNAKDK971TVGDFLKQQL981QKPRPIILDP991ADPTGNLGHN
1001-10361001ARWDLLAKEA1011AACTSALCCM1021GRNGIPIQPW1031PVKAAV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 73 | Prediction (Medium) | - | - |
| 183 | Prediction (Low) | - | - |
| 241 | Prediction (Medium) | - | - |
| 323 | Prediction (Low) | - | - |
| 350 | Prediction (Medium) | - | - |
| 444 | Prediction (Medium) | - | - |
| 449 | Prediction (Low) | - | - |
| 482 | Prediction (Medium) | - | - |
| 644 | Prediction (Low) | - | - |
| 728 | Prediction (Medium) | - | - |
| 781 | Prediction (High) | - | - |
| 788 | Prediction (Medium) | - | - |
| 905 | Prediction (Medium) | - | - |
| 958 | Prediction (Low) | - | - |
| 1013 | Prediction (Medium) | - | - |
| 1018 | Prediction (Medium) | - | - |
| 1019 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 94 | R → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 257 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 328 | C → C | 0.002427 | SNP | Silent | BLCA |
| 340 | W → C | 0.002294 | SNP | Missense Mutation | OV |
| 443 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 449 | C → del | 0.003559 | DEL | In Frame Del | KIRP |
| 869 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 978 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |