Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A7P0TA50 | OAS3 | 2'-5'-oligoadenylate synthetase 3 | Homo sapiens (Human) | 567 aa |
Protein Details: A0A7P0TA50 (OAS3)
Protein Information
| Accession | A0A7P0TA50 |
|---|---|
| Protein Names | 2'-5'-oligoadenylate synthetase 3 |
| Gene Symbol | OAS3 |
| Organism | Homo sapiens (Human) |
| Length | 567 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDLYSTPAAA11LDRFVARRLQ21PRKEFVEKAR31RALGALAAAL41RERGGRLGAA
51-10051APRVLKTVKG61GSSGRGTALK71GGCDSELVIF81LDCFKSYVDQ91RARRAEILSE
101-150101MRASLESWWQ111NPVPGLRLTF121PEQSVPGALQ131FRLTSVDLED141WMDVSLVPAF
151-200151NVLGQAGSGV161KPKPQVYSTL171LNSGCQGGEH181AACFTELRRN191FVNIRPAKLK
201-250201NLILLVKHWY211HQVCLQGLWK221ETLPPVYALE231LLTIFAWEQG241CKKDAFSLAE
251-300251GLRTVLGLIQ261QHQHLCVFWT271VNYGFEDPAV281GQFLQRQLKR291PRPVILDPAD
301-350301PTWDLGNGAA311WHWDLLAQEA321ASCYDHPCFL331RGMGDPVQSW341KGPGLPRAGC
351-400351SGLGHPIQLD361PNQKTPENSK371SLNAVYPRAG381SKPPSCPAPG391PTGAASIVPS
401-450401VPGMALDLSQ411IPTKELDRFI421QDHLKPSPQF431QEQVKKAIDI441ILRCLHENCV
451-500451HKASRVSKGG461SFGRGTDLRD471GCDVELIIFL481NCFTDYKDQG491PRRAEILDEM
501-550501RAQLESWWQD511QVPSLSLQFP521EQNVPEALQF531QLVSTALKSW541TDVSLLPAFD
551-567551AVGLLEAPHQ561WLPGGRA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 73 | - | - | - |
Deep-Palm: 0.90
|
|
| 83 | - | - | - |
Deep-Palm: 0.96
|
|
| 175 | - | - | - |
Deep-Palm: 0.90
|
|
| 183 | - | - | - |
Deep-Palm: 0.90
|
|
| 214 | - | - | - |
Deep-Palm: 0.83
|
|
| 241 | - | - | - |
Deep-Palm: 0.97
|
|
| 266 | - | - | - |
Deep-Palm: 0.39
|
|
| 323 | - | - | - |
Deep-Palm: 0.22
|
|
| 328 | - | - | - |
Deep-Palm: 0.40
|
|
| 350 | - | - | - |
Deep-Palm: 0.84
|
|
| 386 | - | - | - |
Deep-Palm: 0.93
|
|
| 444 | - | - | - |
Deep-Palm: 0.85
|
|
| 449 | - | - | - |
Deep-Palm: 0.79
|
|
| 472 | - | - | - |
Deep-Palm: 0.62
|
|
| 482 | - | - | - |
Deep-Palm: 0.77
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
PC3
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 94 | R → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 257 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 328 | C → C | 0.002427 | SNP | Silent | BLCA |
| 340 | W → C | 0.002294 | SNP | Missense Mutation | OV |
| 443 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 449 | C → del | 0.003559 | DEL | In Frame Del | KIRP |
| 869 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 978 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |