Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A8I5KRT8 | AFG3L2 | AFG3 like matrix AAA peptidase … | Homo sapiens (Human) | 120 aa |
Protein Details: A0A8I5KRT8 (AFG3L2)
Protein Information
| Accession | A0A8I5KRT8 |
|---|---|
| Protein Names | AFG3 like matrix AAA peptidase subunit 2 |
| Gene Symbol | AFG3L2 |
| Organism | Homo sapiens (Human) |
| Length | 120 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAHRCLRLWG11RGGCWPRGLQ21QLLVPGGVGP31GEQPCLRTLY41RFVTTQARAS
51-10051RNSLLTDIIA61AYQRFCSRPP71KGFEKYFPNG81KNGKKASEPK91EVMGEKKGRQ
101-120101IGSRQQAFCS111SDLYTRKNSC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.04
|
|
| 14 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.94
|
|
| 35 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.97
|
|
| 66 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.78
|
|
| 109 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.08
|
|
| 120 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
PC3
Specificity: 0.667
2/2 (100.0%)
1
frontal cortex
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 106 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 468 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |