Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A8I5KVV1 | AFG3L2 | AFG3 like matrix AAA peptidase … | Homo sapiens (Human) | 772 aa |
Protein Details: A0A8I5KVV1 (AFG3L2)
Protein Information
| Accession | A0A8I5KVV1 |
|---|---|
| Protein Names | AFG3 like matrix AAA peptidase subunit 2 |
| Gene Symbol | AFG3L2 |
| Organism | Homo sapiens (Human) |
| Length | 772 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
2
PC3 cells
Specificity: 0.667
2/4 (50.0%)
1
Prefrontal cortex
Specificity: 0.333
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAHRCLRLWG11RGGCWPRGLQ21QLLVPGGVGP31GEQPCLRTLY41RFVTTQARAS
51-10051RNSLLTDIIA61AYQRFCSRPP71KGFEKYFPNG81KNGKKASEPK91EVMGEKKESK
101-150101PAATTRSSGG111GGGGGGKRGG121KKDDSHWWSR131FQKGDIPWDD141KDFRMFFLWT
151-200151ALFWGGVMFY161LLLKRSGREI171TWKDFVNNYL181SKGVQYVWFN191IGSVDTFERN
201-250201LETLQQELGI211EGENRVPVVY221IAESDGSFLL231SMLPTVLIIA241FLLYTIRRGP
251-300251AGIGRTGRGM261GGLFSVGETT271AKVLKDEIDV281KFKDVAGCEE291AKLEIMEFVN
301-350301FLKNPKQYQD311LGAKIPKGAI321LTGPPGTGKT331LLAKATAGEA341NVPFITVSGS
351-400351EFLEMFVGVG361PARVRDLFAL371ARKNAPCILF381IDEIDAVGRK391RGRGNFGGQS
401-450401EQENTLNQLL411VEMDGFNTTT421NVVILAGTNR431PDILDPALLR441PGRFDRQIFI
451-500451GPPDIKGRAS461IFKVHLRPLK471LDSTLEKDKL481ARKLASLTPG491FSGADVANVC
501-550501NEAALIAARH511LSDSINQKHF521EQAIERVIGG531LEKKTQVLQP541EEKKTVAYHE
551-600551AGHAVAGWYL561EHADPLLKVS571IIPRGKGLGY581AQYLPKEQYL591YTKEQLLDRM
601-650601CMTLGGRVSE611EIFFGRITTG621AQDDLRKVTQ631SAYAQIVQFG641MNEKVGQISF
651-700651DLPRQGDMVL661EKPYSEATAR671LIDDEVRILI681NDAYKRTVAL691LTEKKADVEK
701-750701VALLLLEKEV711LDKNDMVELL721GPRPFAEKST731YEEFVEGTGS741LDEDTSLPEG
751-772751LKDWNKEREK761EKEEPPGEKV771AN
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 5 | Prediction (Medium) | - | - |
| 14 | Prediction (Medium) | - | - |
| 35 | Prediction (Medium) | - | - |
| 66 | Prediction (High) | - | - |
| 288 | Prediction (Medium) | - | - |
| 377 | Prediction (High) | - | - |
| 500 | Prediction (Medium) | - | - |
| 601 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 106 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 468 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |