Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A8I5QJR7 | AFG3L2 | AFG3 like matrix AAA peptidase … | Homo sapiens (Human) | 751 aa |
Protein Details: A0A8I5QJR7 (AFG3L2)
Protein Information
| Accession | A0A8I5QJR7 |
|---|---|
| Protein Names | AFG3 like matrix AAA peptidase subunit 2 |
| Gene Symbol | AFG3L2 |
| Organism | Homo sapiens (Human) |
| Length | 751 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
2
PC3 cells
Specificity: 0.667
2/4 (50.0%)
1
Prefrontal cortex
Specificity: 0.333
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAHRCLRLWG11RGGCWPRGLQ21QLLVPGGVGP31GEQPCLRTLY41RFVTTQARAS
51-10051RNSLLTDIIA61AYQRFCSRPP71KGFEKYFPNG81KNGKKASEPK91EVMGEKKESK
101-150101PAATTRSSGG111GGGGGGKRGG121KKDDSHWWSR131FQKGDIPWDD141KDFRMFFLWT
151-200151ALFWGGVMFY161LLLKRSGREI171TWKDFVNNYL181SKGVVDRLEV191VNKRFVRVTF
201-250201TPGKTPVDGQ211YVWFNIGSVD221TFERNLETLQ231QELGIEGENR241VPVVYIAESD
251-300251GSFLLSMLPT261VLIIAFLLYT271IRRGPAGIGR281TGRGMGGLFS291VGETTAKVLK
301-350301DEIDVKFKDV311AGCEEAKLEI321MEFVNFLKNP331KQYQDLGAKI341PKVRDLFALA
351-400351RKNAPCILFI361DEIDAVGRKR371GRGNFGGQSE381QENTLNQLLV391EMDGFNTTTN
401-450401VVILAGTNRP411DILDPALLRP421GRFDRQIFIG431PPDIKGRASI441FKVHLRPLKL
451-500451DSTLEKDKLA461RKLASLTPGF471SGADVANVCN481EAALIAARHL491SDSINQKHFE
501-550501QAIERVIGGL511EKKTQVLQPE521EKKTVAYHEA531GHAVAGWYLE541HADPLLKVSI
551-600551IPRGKGLGYA561QYLPKEQYLY571TKEQLLDRMC581MTLGGRVSEE591IFFGRITTGA
601-650601QDDLRKVTQS611AYAQIVQFGM621NEKVGQISFD631LPRQGDMVLE641KPYSEATARL
651-700651IDDEVRILIN661DAYKRTVALL671TEKKADVEKV681ALLLLEKEVL691DKNDMVELLG
701-750701PRPFAEKSTY711EEFVEGTGSL721DEDTSLPEGL731KDWNKEREKE741KEEPPGEKVA
751-751751N
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 5 | Prediction (Medium) | - | - |
| 14 | Prediction (Medium) | - | - |
| 35 | Prediction (Medium) | - | - |
| 66 | Prediction (High) | - | - |
| 313 | Prediction (Medium) | - | - |
| 356 | Prediction (High) | - | - |
| 479 | Prediction (Medium) | - | - |
| 580 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 106 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 468 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |