Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A8Q3WL10 | CXCR4 | C-X-C chemokine receptor type 4 | Homo sapiens (Human) | 348 aa |
Protein Details: A0A8Q3WL10 (CXCR4)
Protein Information
| Accession | A0A8Q3WL10 |
|---|---|
| Protein Names | C-X-C chemokine receptor type 4 |
| Gene Symbol | CXCR4 |
| Organism | Homo sapiens (Human) |
| Length | 348 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
Jurkat T cells
Specificity: 1.000
3/25 (12.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MIYTSDNYTE11EMGSGDYDSM21KEPCFREENA31NFNKIFLPTI41YSIIFLTGIV
51-10051GNGLVILVMG61YQKKLRSMTD71KYRLHLSVAD81LLFVITLPFW91AVDAVANWYF
101-150101GNFLCKAVHV111IYTVNLYSSV121LILAFISLDR131YLAIVHATNS141QRPRKLLAEK
151-200151VVYVGVWIPA161LLLTIPDFIF171ANVSEADDRY181ICDRFYPNDL191WVVVFQFQHI
201-250201MVGLILPGIV211ILSCYCIIIS221KLSHSKGHQK231RKALKTTVIL241ILAFFACWLP
251-300251YYIGISIDSF261ILLEIIKQGC271EFENTVHKWI281SITEALAFFH291CCLNPILYAF
301-348301LGAKFKTSAQ311HALTSVSRGS321SLKILSKGKR331GGHSSVSTES341ESSSFHSS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 214 | Prediction (Medium) | - | - |
| 216 | Prediction (High) | - | - |
| 270 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 30 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 30 | R → C | 0.001969 | SNP | Missense Mutation | LGG |
| 76 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 109 | C → Hfs*6 | 0.002294 | INS | Nonsense Mutation | OV |
| 235 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 320 | V → Cfs*24 | 0.002033 | INS | Frame Shift Ins | LUSC |