Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A8V8TM76 | TAP1 | ABC-type antigen peptide transporter (EC … | Homo sapiens (Human) | 829 aa |
Protein Details: A0A8V8TM76 (TAP1)
Protein Information
| Accession | A0A8V8TM76 |
|---|---|
| Protein Names | ABC-type antigen peptide transporter (EC 7.4.2.14) |
| Gene Symbol | TAP1 |
| Organism | Homo sapiens (Human) |
| Length | 829 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.600
3/4 (75.0%)
2
DU145 cells
Specificity: 0.400
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASSRCPAPR11GCRCLPGASL21AWLGTVLLLL31ADWVLLRTAL41PRIFSLLVPT
51-10051ALPLLRVWAV61GLSRWAVLWL71GACGVLRATV81GSKSENAGAQ91GWLAALKPLA
101-150101AALGLALPGL111ALFRELISWG121APGSADSTRL131LHWGSHPTAF141VVSYAAALPA
151-200151AALWHKLGSL161WVPGGQGGSG171NPVRRLLGCL181GSETRRLSLF191LVLVVLSSLG
201-250201EMAIPFFTGR211LTDWILQDGS221ADTFTRNLTL231MSILTIASAV241LEFVGDGIYN
251-300251NTMGHVHSHL261QGEVFGAVLR271QETEFFQQNQ281TGNIMSRVTE291DTSTLSDSLS
301-350301ENLSLFLWYL311VRGLCLLGIM321LWGSVSLTMV331TLITLPLLFL341LPKKVGKWYQ
351-400351LLEVQVRESL361AKSSQVAIEA371LSAMPTVRSF381ANEEGEAQKF391REKLQEIKTL
401-450401NQKEAVAYAV411NSWTTSISGM421LLKVGILYIG431GQLVTSGAVS441SGNLVTFVLY
451-500451QMQFTQAVEV461LLSIYPRVQK471AVGSSEKIFE481YLDRTPRCPP491SGLLTPLHLE
501-550501GLVQFQDVSF511AYPNRPDVLV521LQGLTFTLRP531GEVTALVGPN541GSGKSTVAAL
551-600551LQNLYQPTGG561QLLLDGKPLP571QYEHRYLHRQ581VAAVGQEPQV591FGRSLQENIA
601-650601YGLTQKPTME611EITAAAVKSG621AHSFISGLPQ631GYDTEVDEAG641SQLSGGQRQA
651-700651VALARALIRK661PCVLILDDAT671SALDANSQLQ681SLMKQRVCGE691VLRMGNVGVL
701-750701GVVSRASSDP711VRWSSSCTKA721LSGTPAQCFS731SPSTSAWWSR741LTTSSFWKEA
751-800751LSGRGEPTSS761SWRKRGATGP771WCRLLQMLQN781ESLLRPAHSI791SLPFLLSVVE
801-829801NHSCRVGSCL811QDELLEICLE821CVTSFPSSS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 6 | Prediction (Medium) | - | - |
| 12 | Prediction (Medium) | - | - |
| 14 | Prediction (Low) | - | - |
| 73 | Prediction (High) | - | - |
| 179 | Prediction (High) | - | - |
| 315 | Prediction (Low) | - | - |
| 662 | Prediction (High) | - | - |
| 688 | Prediction (Medium) | - | - |
| 728 | Prediction (Medium) | - | - |
| 772 | Prediction (High) | - | - |
| 804 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 544 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 544 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 547 | R → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 575 | R → C | 0.002294 | SNP | Missense Mutation | OV |
| 589 | R → C | 0.002545 | SNP | Missense Mutation | GBM |