Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A0A8V8TN05 | SLC44A1 | Choline transporter-like protein | Homo sapiens (Human) | 724 aa |
Protein Details: A0A8V8TN05 (SLC44A1)
Protein Information
| Accession | A0A8V8TN05 |
|---|---|
| Protein Names | Choline transporter-like protein |
| Gene Symbol | SLC44A1 |
| Organism | Homo sapiens (Human) |
| Length | 724 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCCSSASSA11AQSSKREWKP21LEDRSCTDIP31WLLLFILFCI41GMGFICGFSI
51-10051ATGAAARLVS61GYDSYGNICG71QKNTKLEAIP81NSGMDHTQRK91YVFFLDPCNL
101-150101DLINRKIKSV111ALCVAACPRQ121ELKTLSDVQK131FAEINGSALC141SYNLKPSEYT
151-200151TSPKSSVLCP161KLPVPASAPI171PFFHRCAPVN181ISCYAKFAEA191LITFVSDNSV
201-250201LHRLISGVMT211SKEIILGLCL221LSLVLSMILM231VIIRYISRVL241VWILTILVIL
251-300251GSLGGTGVLW261WLYAKQRRSP271KETVTPEQLQ281IAEDNLRALL291IYAISATVFT
301-350301VILFLIMLVM311RKRVALTIAL321FHVAGKVFIH331LPLLVFQPFW341TFFALVLFWV
351-400351YWIMTLLFLG361TTGSPVQNEQ371GFVEFKISGP381LQYMWWYHVV391GLIWISEFIL
401-450401ACQQMTVAGA411VVTYYFTRDK421RNLPFTPILA431SVNRLIRYHL441GTVAKGSFII
451-500451TLVKIPRMIL461MYIHSQLKGK471ENACARCVLK481SCICCLWCLE491KCLNYLNQNA
501-550501YTATAINSTN511FCTSAKDAFV521ILVENALRVA531TINTVGDFML541FLGKVLIVCS
551-600551TGLAGIMLLN561YQQDYTVWVL571PLIIVCLFAF581LVAHCFLSIY591EMVVDVLFLC
601-650601FAIDTKYNDG611SPGREFYMDK621VLMEFVENSR631KAMKEAGKGG641VADSRELKPM
651-700651VGGDEEVAAL661QEFHFHFLSL671SVFTDCTSSG681EAFVICITQD691MLLFLFVCLP
701-724701ITWMAEFLSQ711LRPPSIKASG721ASSA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.03
|
|
| 4 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
|
| 26 | - | - | - |
Deep-Palm: 0.86
|
|
| 39 | - | - | - |
Deep-Palm: 0.52
|
|
| 46 | Choline transporter-like | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.44
|
|
| 69 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.88
|
|
| 98 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.92
Deep-Palm: 0.84
|
|
| 113 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.95
Deep-Palm: 0.95
|
|
| 117 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.95
Deep-Palm: 0.97
|
|
| 140 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.77
Deep-Palm: 0.86
|
|
| 159 | - | - | - |
Deep-Palm: 0.94
|
|
| 176 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.71
|
|
| 183 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.29
|
|
| 219 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.97
|
|
| 402 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.11
|
|
| 474 | - | - | - |
Deep-Palm: 0.68
|
|
| 477 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.73
|
|
| 482 | - | - |
Jurkat T
(32651440)
|
GPS-Palm: 0.95
Deep-Palm: 0.80
|
|
| 484 | - | - |
Jurkat T
(32651440)
|
GPS-Palm: 0.95
Deep-Palm: 0.61
|
|
| 485 | - | - |
Jurkat T
(32651440)
|
GPS-Palm: 0.95
Deep-Palm: 0.62
|
|
| 488 | - | - |
Jurkat T
(32651440)
|
GPS-Palm: 0.84
Deep-Palm: 0.59
|
|
| 492 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.53
|
|
| 512 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.42
|
|
| 549 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.55
|
|
| 576 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.13
|
|
| 585 | - | - | - |
Deep-Palm: 0.18
|
|
| 600 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.14
|
|
| 676 | - | - | - |
Deep-Palm: 0.10
|
|
| 686 | - | - | - |
Deep-Palm: 0.21
|
|
| 698 | - | - | - |
Deep-Palm: 0.13
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
PC3
Specificity: 0.400
4/4 (100.0%)
1
DU145 cell
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Cerebral Cortex (Mass)
Specificity: 0.400
4/4 (100.0%)
1
LNCaP cells (Mass)
Specificity: 0.100
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 24 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 46 | C → R | 0.001014 | SNP | Missense Mutation | BRCA |
| 69 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 98 | C → R | 0.001969 | SNP | Missense Mutation | HNSC |
| 98 | C → C | 0.001764 | SNP | Silent | LUAD |
| 159 | C → F | 0.002294 | SNP | Missense Mutation | OV |
| 175 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 176 | C → G | 0.001887 | SNP | Missense Mutation | UCEC |
| 226 | S → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 311 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 339 | F → C | 0.008130 | SNP | Missense Mutation | THYM |
| 415 | Y → C | 0.010870 | SNP | Missense Mutation | ACC |
| 434 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 437 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 437 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 441 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 447 | S → C | 0.002294 | SNP | Missense Mutation | OV |