Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A0A994J5Q6 DPP6 A-type potassium channel modulatory protein … Homo sapiens (Human) 540 aa

Protein Details: A0A994J5Q6 (DPP6)

Protein Information
Accession A0A994J5Q6
Protein Names A-type potassium channel modulatory protein DPP6 (Dipeptidyl aminopeptidase-like protein 6) (Dipeptidyl peptidase 6) (Dipeptidyl peptidase VI)
Gene Symbol DPP6
Organism Homo sapiens (Human)
Length 540 aa
Isoforms No isoforms
Related PMIDs 26876311
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Prefrontal cortex
Specificity: 1.000
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MELPTYTGSI11YPTVKPYHYP21KAGSENPSIS31LHVIGLNGPT41HDLEMMPPDD
51-10051PRMREYYITM61VKWATSTKVA71VTWLNRAQNV81SILTLCDATT91GVCTKKHEDE
101-150101SEAWLHRQNE111EPVFSKDGRK121FFFIRAIPQG131GRGKFYHITV141SSSQPNSSND
151-200151NIQSITSGDW161DVTKILAYDE171KGNKIYFLST181EDLPRRRQLY191SANTVGNFNR
201-250201QCLSCDLVEN211CTYFSASFSH221SMDFFLLKCE231GPGVPMVTVH241NTTDKKKMFD
251-300251LETNEHVKKA261INDRQMPKVE271YRDIEIDDYN281LPMQILKPAT291FTDTTHYPLL
301-350301LVVDGTPGSQ311SVAEKFEVSW321ETVMVSSHGA331VVVKCDGRGS341GFQGTKLLHE
351-400351VRRRLGLLEE361KDQMEAVRTM371LKEQYIDRTR381VAVFGKDYGG391YLSTYILPAK
401-450401GENQGQTFTC411GSALSPITDF421KLYASAFSER431YLGLHGLDNR441AYEMTKVAHR
451-500451VSALEEQQFL461IIHPTADEKI471HFQHTAELIT481QLIRGKANYS491LQIYPDESHY
501-540501FTSSSLKQHL511YRSIINFFVE521CFRIQDKLLT531VTAKEDEEED
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
86 Prediction (Low) - -
93 Prediction (Low) - -
202 Prediction (Low) - -
205 Prediction (Low) - -
521 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
200 Y → C 0.002288 SNP Missense Mutation STAD
251 G → C 0.002506 SNP Missense Mutation COAD
265 C → S 0.001764 SNP Missense Mutation LUAD
265 C → G 0.002506 SNP Missense Mutation COAD
315 Y → C 0.002545 SNP Missense Mutation GBM
322 R → C 0.002288 SNP Missense Mutation STAD
322 R → C 0.001887 SNP Missense Mutation UCEC
501 Y → C 0.005618 SNP Missense Mutation PAAD
527 C → Y 0.002288 SNP Missense Mutation STAD
536 C → S 0.001764 SNP Missense Mutation LUAD
550 F → C 0.001764 SNP Missense Mutation LUAD
663 R → C 0.002747 SNP Missense Mutation LIHC
692 V → Cfs*5 0.001887 DEL Frame Shift Del UCEC
705 R → C 0.002288 SNP Missense Mutation STAD
767 Y → C 0.002288 SNP Missense Mutation STAD
829 S → C 0.005435 SNP Missense Mutation ESCA