Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A1L0T0 ILVBL; AHAS; HACL2 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) … Homo sapiens (Human) 632 aa

Protein Details: A1L0T0 (ILVBL)

Protein Information
Accession A1L0T0
Protein Names 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) (Acetolactate synthase-like protein) (IlvB-like protein)
Gene Symbol ILVBL; AHAS; HACL2
Organism Homo sapiens (Human)
Length 632 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.828
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.828
24/46 (52.2%)
3
PC3 cells
Specificity: 0.103
3/4 (75.0%)
2
DU145 cells
Specificity: 0.069
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501METPAAAAPA11GSLFPSFLLL21ACGTLVAALL31GAAHRLGLFY41QLLHKVDKAS
51-10051VRHGGENVAA61VLRAHGVRFI71FTLVGGHISP81LLVACEKLGI91RVVDTRHEVT
101-150101AVFAADAMAR111LSGTVGVAAV121TAGPGLTNTV131TAVKNAQMAQ141SPILLLGGAA
151-200151STLLQNRGAL161QAVDQLSLFR171PLCKFCVSVR181RVRDIVPTLR191AAMAAAQSGT
201-250201PGPVFVELPV211DVLYPYFMVQ221KEMVPAKPPK231GLVGRVVSWY241LENYLANLFA
251-300251GAWEPQPEGP261LPLDIPQASP271QQVQRCVEIL281SRAKRPLMVL291GSQALLTPTS
301-350301ADKLRAAVET311LGVPCFLGGM321ARGLLGRNHP331LHIRENRSAA341LKKADVIVLA
351-400351GTVCDFRLSY361GRVLSHSSKI371IIVNRNREEM381LLNSDIFWKP391QEAVQGDVGS
401-450401FVLKLVEGLQ411GQTWAPDWVE421ELREADRQKE431QTFREKAAMP441VAQHLNPVQV
451-500451LQLVEETLPD461NSILVVDGGD471FVGTAAHLVQ481PRGPLRWLDP491GAFGTLGVGA
501-550501GFALGAKLCR511PDAEVWCLFG521DGAFGYSLIE531FDTFVRHKIP541VMALVGNDAG
551-600551WTQISREQVP561SLGSNVACGL571AYTDYHKAAM581GLGARGLLLS591RENEDQVVKV
601-632601LHDAQQQCRD611GHPVVVNILI621GRTDFRDGSI631AV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
85 Prediction (Medium) - -
173 Prediction (High) - -
176 Prediction (High) - -
276 Prediction (Low) - -
315 Prediction (Medium) - -
354 Prediction (Medium) - -
509 Prediction (Low) - -
517 Prediction (Low) - -
568 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
85 C → Y 0.001887 SNP Missense Mutation UCEC
91 R → C 0.002506 SNP Missense Mutation COAD
91 R → C 0.001887 SNP Missense Mutation UCEC
275 R → C 0.001887 SNP Missense Mutation UCEC
324 L → Cfs*2 0.002288 DEL Frame Shift Del STAD
362 R → C 0.001887 SNP Missense Mutation UCEC