Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A1L0T0 | HACL2 | 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) … | Homo sapiens (Human) | 632 aa |
Protein Details: A1L0T0 (HACL2)
Protein Information
| Accession | A1L0T0 |
|---|---|
| Protein Names | 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) (Acetolactate synthase-like protein) (IlvB-like protein) |
| Gene Symbol | HACL2 |
| Organism | Homo sapiens (Human) |
| Length | 632 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501METPAAAAPA11GSLFPSFLLL21ACGTLVAALL31GAAHRLGLFY41QLLHKVDKAS
51-10051VRHGGENVAA61VLRAHGVRFI71FTLVGGHISP81LLVACEKLGI91RVVDTRHEVT
101-150101AVFAADAMAR111LSGTVGVAAV121TAGPGLTNTV131TAVKNAQMAQ141SPILLLGGAA
151-200151STLLQNRGAL161QAVDQLSLFR171PLCKFCVSVR181RVRDIVPTLR191AAMAAAQSGT
201-250201PGPVFVELPV211DVLYPYFMVQ221KEMVPAKPPK231GLVGRVVSWY241LENYLANLFA
251-300251GAWEPQPEGP261LPLDIPQASP271QQVQRCVEIL281SRAKRPLMVL291GSQALLTPTS
301-350301ADKLRAAVET311LGVPCFLGGM321ARGLLGRNHP331LHIRENRSAA341LKKADVIVLA
351-400351GTVCDFRLSY361GRVLSHSSKI371IIVNRNREEM381LLNSDIFWKP391QEAVQGDVGS
401-450401FVLKLVEGLQ411GQTWAPDWVE421ELREADRQKE431QTFREKAAMP441VAQHLNPVQV
451-500451LQLVEETLPD461NSILVVDGGD471FVGTAAHLVQ481PRGPLRWLDP491GAFGTLGVGA
501-550501GFALGAKLCR511PDAEVWCLFG521DGAFGYSLIE531FDTFVRHKIP541VMALVGNDAG
551-600551WTQISREQVP561SLGSNVACGL571AYTDYHKAAM581GLGARGLLLS591RENEDQVVKV
601-632601LHDAQQQCRD611GHPVVVNILI621GRTDFRDGSI631AV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 22 | - | - | - |
Deep-Palm: 0.98
|
|
| 85 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.98
|
|
| 173 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.88
|
|
| 176 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.88
|
|
| 276 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.70
Deep-Palm: 0.98
|
|
| 315 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 354 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.98
|
|
| 509 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.95
|
|
| 517 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.92
|
|
| 568 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.90
|
|
| 608 | - | - | - |
Deep-Palm: 0.53
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
PC3
Specificity: 0.429
3/3 (100.0%)
2
LNCaP
Specificity: 0.286
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP cells (Mass)
Specificity: 0.286
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.