Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A2A3R5 | RPS6; hCG_1741512 | 40S ribosomal protein S6 | Homo sapiens (Human) | 218 aa |
Protein Details: A2A3R5 (RPS6)
Protein Information
| Accession | A2A3R5 |
|---|---|
| Protein Names | 40S ribosomal protein S6 |
| Gene Symbol | RPS6; hCG_1741512 |
| Organism | Homo sapiens (Human) |
| Length | 218 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.828
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.828
24/46 (52.2%)
3
PC3 cells
Specificity: 0.103
3/4 (75.0%)
1
Endothelial cells
Specificity: 0.034
1/2 (50.0%)
1
Cerebral cortex
Specificity: 0.034
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MATEVAADAL11GEEWKGYVVR21ISGGNDKQGF31PMKQGVLTHG41RVRLLLSKGH
51-10051SCYRPRRTGE61RKRKSVRGCI71VDANLSVLNL81VIVKKGEKDI91PGLTDTTVPR
101-150101RLGPKRASRI111RKLFNLSKED121DVRQYVVRKP131LNKEGKKPRT141KAPKIQRLVT
151-200151PRVLQHKRRR161IALKKQRTKK171NKEEAAEYAK181LLAKRMKEAK191EKRQEQIAKR
201-218201RRLSSLRAST211SKSESSQK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 52 | Prediction (High) | - | - |
| 69 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 22 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 31 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 131 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 183 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 191 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 191 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 232 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 236 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |