Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A2ANZ2 | C9orf72 | C9orf72, member of C9orf72-SMCR8 complex | Mus musculus (Mouse) | 317 aa |
Protein Details: A2ANZ2 (C9orf72)
Protein Information
| Accession | A2ANZ2 |
|---|---|
| Protein Names | C9orf72, member of C9orf72-SMCR8 complex |
| Gene Symbol | C9orf72 |
| Organism | Mus musculus (Mouse) |
| Length | 317 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEDQGQSIIP11MLTGEVIPVM21ELLASMKSHS31VPEDIDIADT41VLNDDDIGDS
51-10051CHEGFLLNAI61SSHLQTCGCS71VVVGSSAEKV81NKIVRTLCLF91LTPAERKCSR
101-150101LCEAESSFKY111ESGLFVQGLL121KDATGSFVLP131FRQVMYAPYP141TTHIDVDVNT
151-200151VKQMPPCHEH161IYNQRRYMRS171ELTAFWRATS181EEDMAQDTII191YTDESFTPDL
201-250201NIFQDVLHRD211TLVKAFLDQV221FHLKPGLSLR231STFLAQFLLI241LHRKALTLIK
251-300251YIEDDTQKGK261KPFKSLRNLK271IDLDLTAEGD281LNIIMALAEK291IKPGLHSFIF
301-317301GRPFYTSVQE311RDVLMTF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 51 | Guanine nucleotide exchange factor C9orf72 | - | - |
Deep-Palm: 0.16
|
|
| 67 | - | - | - |
Deep-Palm: 0.78
|
|
| 69 | - | - | - |
Deep-Palm: 0.73
|
|
| 88 | SWISSPALM DBPTM CYSMODDB | C9orf72-like protein family |
Forebrain
(28680068)
| - |
GPS-Palm: 0.95
Deep-Palm: 0.95
|
| 98 | - | - | - |
Deep-Palm: 0.91
|
|
| 102 | - | - | - |
Deep-Palm: 0.90
|
|
| 157 | - | - | - |
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 272 | F → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 303 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 329 | R → C | 0.002506 | SNP | Missense Mutation | COAD |