Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A2AVR6 Acot11 Acyl-coenzyme A thioesterase 11 (EC … Mus musculus (Mouse) 614 aa

Protein Details: A2AVR6 (Acot11)

Protein Information
AccessionA2AVR6
Protein NamesAcyl-coenzyme A thioesterase 11 (EC 3.1.2.2) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (Palmitoyl-coenzyme A thioesterase)
Gene SymbolAcot11
OrganismMus musculus (Mouse)
Length614 aa
IsoformsNo isoforms
Related PMIDs 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRARRSSPSG11KADVSLASQL21RRSPPCTFLG31QGFASMFSNR41TSRKSISHPE
51-10051SGDPPTMAEG61EGYRNPTEVQ71MSQLVLPCHT81NHRGELSIGQ91LLKWIDTTAC
101-150101LSAERHAGCP111CVTASMDDIY121FDHTISVGQV131VNIKAKVNRA141FNSSMEVGIQ
151-200151VVSEDLCSEK161QWSVCKALAT171FVAHRELSKV181KLKQVIPLTE191EEKTEHGVAA
201-250201ERRRMRLVYA211DTIKDLLTHC221VIQDDLDKDC231SNMVPAEKTR241VESVELVLPP
251-300251HANHQGNTFG261GQIMAWMENV271ATIAASRLCH281AHPTLKAIEM291FHFRGPSQVG
301-350301DRLVLKAIVN311NAFKHSMEVG321VCVEAYRQEA331ETQRRHINSA341FMTFVVLDKD
351-400351DQPQKLPWIR361PQPGEGERRY371REASARKKIR381LDRKYLVSCK391QAEVALSVPW
401-450401DPSNQVYLSY411YNVSSLKTLM421AKDNWVLSVE431ISEVRLYILE441EDFLSFHLEM
451-500451VVNVDAAQVF461QLLSDLRRRP471EWDKHYRSVE481LVQQVDEDDA491IYHVISPALS
501-550501GNTKPQDFVI511LASRRKPCDN521GDPYVIALRS531VTLPTHHETP541EYQRGETLCS
551-600551GFCLWREGDQ561MTKVSYYNQA571TPGFLNYVTT581NVSGLSSEFY591NTFKACESFL
601-614601LDNRNDLAPS611LQTL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
26 - - -
Deep-Palm: 0.93
78 - - -
Deep-Palm: 0.96
100 - - -
Deep-Palm: 0.96
109 - - -
Deep-Palm: 0.09
111 - - -
Deep-Palm: 0.11
157 - - -
Deep-Palm: 0.63
165 - - -
Deep-Palm: 0.94
220 - -
Brain (35358180)
Deep-Palm: 0.56
230 - - -
Deep-Palm: 0.60
279 - - -
Deep-Palm: 0.35
322 - - -
Deep-Palm: 0.42
389 - - -
Deep-Palm: 0.96
518 - - -
Deep-Palm: 0.87
549 - - -
Deep-Palm: 0.53
553 SWISSPALM DBPTM CYSMODDB START domain
Forebrain (28680068)
-
GPS-Palm: 0.90
Deep-Palm: 0.69
596 - - -
GPS-Palm: 0.91
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
17
Brain tissue (Mass)
Specificity: 1.000
17/56 (30.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine