Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A2VCT2 | OGDH | 2-oxoglutarate dehydrogenase complex component E1 … | Homo sapiens (Human) | 636 aa |
Protein Details: A2VCT2 (OGDH)
Protein Information
| Accession | A2VCT2 |
|---|---|
| Protein Names | 2-oxoglutarate dehydrogenase complex component E1 (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase) |
| Gene Symbol | OGDH |
| Organism | Homo sapiens (Human) |
| Length | 636 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.750
3/4 (75.0%)
1
DU145 cells
Specificity: 0.250
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501CIQPGEAQPN11VDKLVEDHLA21VQSLIRAYQV31RGHHIAKLDP41LGISCVNFDD
51-10051APVTVSSNVD61LAVFKERLRM71LTVGGFYGLD81ESDLDKVFHL91PTTTFIGGQE
101-150101SALPLREIIR111RLEMAYCQHI121GVEFMFINDL131EQCQWIRQKF141ETPGIMQFTN
151-200151EEKRTLLARL161VRSTRFEEFL171QRKWSSEKRF181GLEGCEVLIP191ALKTIIDKSS
201-250201ENGVDYVIMG211MPHRGRLNVL221ANVIRKELEQ231IFCQFDSKLE241AADEGSGDVK
251-300251YHLGMYHRRI261NRVTDRNITL271SLVANPSHLE281AADPVVMGKT291KAEQFYCGDT
301-350301EGKKVMSILL311HGDAAFAGQG321IVYETFHLSD331LPSYTTHGTV341HVVVNNQIGF
351-400351TTDPRMARSS361PYPTDVARVV371NAPIFHVNSD381DPEAVMYVCK391VAAEWRSTFH
401-450401KDVVVDLVCY411RRNGHNEMDE421PMFTQPLMYK431QIRKQKPVLQ441KYAELLVSQG
451-500451VVNQPEYEEE461ISKYDKICEE471AFARSKDEKI481LHIKHWLDSP491WPGFFTLDGQ
501-550501PRSMSCPSTG511LTEDILTHIG521NVASSVPVEN531FTIHGGLSRI541LKTRGEMVKN
551-600551RTVDWALAEY561MAFGSLLKEG571IHIRLSGQDV581ERGTFSHRHH591VLHDQNVDKR
601-636601TCIPMNHLWP611NQAPYTVCNS621SLSEYGVLGF631ELCFTR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 1 | Prediction (High) | - | - |
| 117 | Prediction (Low) | - | - |
| 133 | Prediction (Medium) | - | - |
| 185 | Prediction (High) | - | - |
| 233 | Prediction (Medium) | - | - |
| 297 | Prediction (Low) | - | - |
| 409 | Prediction (Medium) | - | - |
| 468 | Prediction (Medium) | - | - |
| 506 | Prediction (Medium) | - | - |
| 633 | Prediction (High) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 41 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 81 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 81 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 277 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 283 | C → C | 0.001887 | SNP | Silent | UCEC |
| 604 | C → C | 0.001764 | SNP | Silent | LUAD |
| 653 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 686 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 700 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 713 | Y → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 769 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 794 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 864 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 904 | C → C | 0.001969 | SNP | Silent | LGG |
| 909 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |