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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A6NI79 CCDC69 Coiled-coil domain-containing protein 69 Homo sapiens (Human) 296 aa

Protein Details: A6NI79 (CCDC69)

Protein Information
AccessionA6NI79
Protein NamesCoiled-coil domain-containing protein 69
Gene SymbolCCDC69
OrganismHomo sapiens (Human)
Length296 aa
IsoformsNo isoforms
Related PMIDs 26111759 33636221
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCRHSRLSS11CKPPKKKRQE21PEPEQPPRPE31PHELGPLNGD41TAITVQLCAS
51-10051EEAERHQKDI61TRILQQHEEE71KKKWAQQVEK81ERELELRDRL91DEQQRVLEGK
101-150101NEEALQVLRA111SYEQEKEALT121HSFREASSTQ131QETIDRLTSQ141LEAFQAKMKR
151-200151VEESILSRNY161KKHIQDYGSP171SQFWEQELES181LHFVIEMKNE191RIHELDRRLI
201-250201LMETVKEKNL211ILEEKITTLQ221QENEDLHVRS231RNQVVLSRQL241SEDLLLTREA
251-296251LEKEVQLRRQ261LQQEKEELLY271RVLGANASPA281FPLAPVTPTE291VSFLAT
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
3 - - -
GPS-Palm: 0.91
Deep-Palm: 0.03
11 - - -
GPS-Palm: 0.85
Deep-Palm: 0.06
48 - - -
Deep-Palm: 0.92
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Primary T cell
Specificity: 0.750
3/3 (100.0%)
1
heart
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
191 R → C 0.001887 SNP Missense Mutation UCEC
248 R → C 0.003460 SNP Missense Mutation CESC