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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A6NNZ2 TUBB8B Tubulin beta 8B Homo sapiens (Human) 444 aa

Protein Details: A6NNZ2 (TUBB8B)

Protein Information
AccessionA6NNZ2
Protein NamesTubulin beta 8B
Gene SymbolTUBB8B
OrganismHomo sapiens (Human)
Length444 aa
IsoformsNo isoforms
Related PMIDs 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTM
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MREIVLTQTG11QCGNQIGAKF21WEVISDEHAI31DSAGTYHGDS41HLQLERINVH
51-10051HHEASGGRYV61PRAVLVDLEP71GTMDSVHSGP81FGQVFRPDNF91ISGQCGAGNN
101-150101WAKGRYTEGA111ELTESVMDVV121RKEAESCDCL131QGFQLTHSLG141GGTGSGMGTL
151-200151LISKIREEYP161DRIINTFSIL171PSPKVSDTVV181EPYNATLSVH191QLIENADETF
201-250201CIDNEALYDI211CSRTLKLPTP221TYGDLNHLVS231ATMSGVTTCL241RFPGQLNADL
251-300251RKLAVNMVPF261PRLHFFMPGF271APLTSRGSQQ281YRALTVAELT291QQMFDAKNMM
301-350301AACDPRHGCY311LTVAAIFRGR321MPMREVDEQM331FNIQDKNSSY341FADWFPDNVK
351-400351TAVCDIPPRG361LKMSATFIGN371NAAIQELFTC381VSEQFTAMFR391RKAFLHWYTG
401-444401EGMDEMEFTE411AESNMNDLVS421EYQQYQDATA431EEEEDEEYAE441EEVA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
12 Tubulin/FtsZ, GTPase domain superfamily OS01G0282866 PROTEIN - -
GPS-Palm: 0.77
Deep-Palm: 0.05
95 - - -
GPS-Palm: 0.75
Deep-Palm: 0.69
127 - - -
GPS-Palm: 0.68
Deep-Palm: 0.76
129 - - -
Deep-Palm: 0.83
201 - - -
Deep-Palm: 0.42
211 - - -
GPS-Palm: 0.79
Deep-Palm: 0.71
239 - - -
GPS-Palm: 0.90
Deep-Palm: 0.97
303 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain -
Unknown (32651440)
cerebral cortex (36430497)
GPS-Palm: 0.84
Deep-Palm: 0.16
309 - - -
GPS-Palm: 0.77
Deep-Palm: 0.43
354 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain -
cerebral cortex (36430497)
GPS-Palm: 0.91
Deep-Palm: 0.70
380 - - -
Deep-Palm: 0.47
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.667
4/4 (100.0%)
1
LNCaP
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.167
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine