Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A6PW80 | EEF1A1 | Elongation factor 1-alpha 1 | Homo sapiens (Human) | 106 aa |
Protein Details: A6PW80 (EEF1A1)
Protein Information
| Accession | A6PW80 |
|---|---|
| Protein Names | Elongation factor 1-alpha 1 |
| Gene Symbol | EEF1A1 |
| Organism | Homo sapiens (Human) |
| Length | 106 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 26876311 31251020 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGKEKTHINI11VVIGHVDSGK21STTTGHLIYK31CGGIDKRTIE41KFEKEAAEMG
51-10051KGSFKYAWVL61DKLKAERERG71ITIDISLWKF81ETSKYYVTII91DAPGHRDFIK
101-106101NMITGT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 31 | Translational (tr)-type GTP-binding domain P-loop containing nucleoside triphosphate hydrolase Translation factor GTPase superfamily members | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.375
3/3 (100.0%)
1
Jurkat T cell
Specificity: 0.125
1/1 (100.0%)
1
frontal cortex
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 29 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 167 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 214 | W → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 291 | S → C | 0.004854 | SNP | Missense Mutation | BLCA |
| 370 | C → C | 0.002288 | SNP | Silent | STAD |
| 411 | C → Lfs*3 | 0.001014 | INS | Frame Shift Ins | BRCA |
| 424 | F → Cfs*3 | 0.002141 | DEL | Frame Shift Del | SKCM |
| 427 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |