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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A7UAK5 Pfkfb3 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 splice variant … Mus musculus (Mouse) 555 aa

Protein Details: A7UAK5 (Pfkfb3)

Protein Information
AccessionA7UAK5
Protein Names6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 splice variant 2 (EC 2.7.1.105, EC 3.1.3.46) (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3)
Gene SymbolPfkfb3
OrganismMus musculus (Mouse)
Length555 aa
IsoformsNo isoforms
Related PMIDs 35477839
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPLELTQSRV11QKIWVPVDHR21PSLPRSCGPK31LTNSPTVIVM41VGLPARGKTY
51-10051ISKKLTRYLN61WIGVPTKVFN71VGEYRREAVK81QYSSYNFFRP91DNEEAMRVRK
101-150101QCALAALRDV111KSYLTKEGGQ121IAVFDATNTT131RERRHMILNF141AKENDFKAFF
151-200151IESVCDDPTV161VASNIMEVKI171SSPDYKDCNS181AEAMDDFMKR191INCYEASYQP
201-250201LDPDKCDRDL211SLIKVIDVGR221RFLVNRVQDH231IQSRIVYYLM241NIHVQPRTIY
251-300251LCRHGENEYN261LQGKIGGDSG271LSSRGKKFAN281ALSKFVEEQN291LKDLRVWTSQ
301-350301LKSTIQTAEA311LRLPYEQWKA321LNEIDAGVCE331ELTYEEIRDT341YPEEYALREQ
351-400351DKYYYRYPTG361ESYQDLVQRL371EPVIMELERQ381ENVLVICHQA391VLRCLLAYFL
401-450401DKSAEEMPYL411KCPLHTVLKL421TPVAYGCRVE431SIYLNVESVS441THRERSEAVK
451-500451IQHFASVVRP461SSYTELDFQS471VESAKQDAKK481GPNPLMRRNS491VTPLASPEPT
501-550501KKPRINSFEE511RVASTSAALP521SCLPPEVPTQ531LPGQPLLGKA541CLRSVCHIFS
551-555551KFSPY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
27 6-phosphofructo-2-kinase - -
Deep-Palm: 0.87
102 - - -
GPS-Palm: 0.95
Deep-Palm: 0.97
155 - - -
Deep-Palm: 0.41
178 - - -
Deep-Palm: 0.04
193 - - -
Deep-Palm: 0.12
206 - - -
Deep-Palm: 0.70
252 - - -
Deep-Palm: 0.20
329 - - -
Deep-Palm: 0.69
387 - - -
Deep-Palm: 0.96
394 - - -
Deep-Palm: 0.89
412 - - -
Deep-Palm: 0.82
427 - - -
Deep-Palm: 0.78
522 - - -
Deep-Palm: 0.97
541 - - -
GPS-Palm: 0.91
Deep-Palm: 0.89
546 - - -
GPS-Palm: 0.94
Deep-Palm: 0.10
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Testis
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine