Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A8K2M0 PSMC4; hCG_43346 26S proteasome regulatory subunit 6B … Homo sapiens (Human) 418 aa

Protein Details: A8K2M0 (PSMC4)

Protein Information
Accession A8K2M0
Protein Names 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4)
Gene Symbol PSMC4; hCG_43346
Organism Homo sapiens (Human)
Length 418 aa
Isoforms No isoforms
Related PMIDs 19137006 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
3
Jurkat T cells
Specificity: 0.500
3/25 (12.0%)
3
PC3 cells
Specificity: 0.500
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEEIGILVEK11AQDEIPALSV21SRPQTGLSFL31GPEPEDLEDL41YSRYKKLQQE
51-10051LEFLEVQEEY61IKDEQKNLKK71EFLHAQEEVK81RIQSIPLVIG91QFLEAVDQNT
101-150101AIVGSTTGSN111YYVRILSTID121RELLKPNASV131ALHKHSNALV141DVLPPEADSS
151-200151IMMLTSDQKP161DVMYADIGGM171DIQKQEVREA181VELPLTHFEL191YKQIGIDPPR
201-250201GVLMYGPPGC211GKTMLAKAVA221HHTTAAFIRV231VGSEFVQKYL241GEGPRMVRDV
251-300251FRLAKENAPA261IIFIDEIDAI271ATKRFDAQTG281ADREVQRILL291ELLNQMDGFD
301-350301QNVNVKVIMA311TNRADTLDPA321LLRPGRLDRK331IEFPLPDRRQ341KRLIFSTITS
351-400351KMNLSEEVDL361EDYVARPDKI371SGADINSICQ381ESGMLAVREN391RYIVLAKDFE
401-418401KAYKTVIKKD411EQEHEFYK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
210 Prediction (High) - -
379 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
108 G → C 0.001887 SNP Missense Mutation UCEC
329 R → C 0.001887 SNP Missense Mutation UCEC
379 C → C 0.005618 SNP Silent PAAD