Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A8K2M0 | PSMC4 | 26S proteasome regulatory subunit 6B … | Homo sapiens (Human) | 418 aa |
Protein Details: A8K2M0 (PSMC4)
Protein Information
| Accession | A8K2M0 |
|---|---|
| Protein Names | 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4) |
| Gene Symbol | PSMC4 |
| Organism | Homo sapiens (Human) |
| Length | 418 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEEIGILVEK11AQDEIPALSV21SRPQTGLSFL31GPEPEDLEDL41YSRYKKLQQE
51-10051LEFLEVQEEY61IKDEQKNLKK71EFLHAQEEVK81RIQSIPLVIG91QFLEAVDQNT
101-150101AIVGSTTGSN111YYVRILSTID121RELLKPNASV131ALHKHSNALV141DVLPPEADSS
151-200151IMMLTSDQKP161DVMYADIGGM171DIQKQEVREA181VELPLTHFEL191YKQIGIDPPR
201-250201GVLMYGPPGC211GKTMLAKAVA221HHTTAAFIRV231VGSEFVQKYL241GEGPRMVRDV
251-300251FRLAKENAPA261IIFIDEIDAI271ATKRFDAQTG281ADREVQRILL291ELLNQMDGFD
301-350301QNVNVKVIMA311TNRADTLDPA321LLRPGRLDRK331IEFPLPDRRQ341KRLIFSTITS
351-400351KMNLSEEVDL361EDYVARPDKI371SGADINSICQ381ESGMLAVREN391RYIVLAKDFE
401-418401KAYKTVIKKD411EQEHEFYK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 210 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.96
|
|
| 379 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.92
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
PC3
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 108 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 329 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 379 | C → C | 0.005618 | SNP | Silent | PAAD |