Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A8MTF1 PI4KA 1-phosphatidylinositol 4-kinase (EC 2.7.1.67) Homo sapiens (Human) 435 aa

Protein Details: A8MTF1 (PI4KA)

Protein Information
AccessionA8MTF1
Protein Names1-phosphatidylinositol 4-kinase (EC 2.7.1.67)
Gene SymbolPI4KA
OrganismHomo sapiens (Human)
Length435 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGYVREYILW11AASKSQLLAH21QFIWNMKTNI31YLDEEGHQKD41PDIGDLLDQL
51-10051VEEITGSLSG61PAKDFYQREF71DFFNKITNVS81AIIKPYPKGD91ERKKACLSAL
101-150101SEVKVQPGCY111LPSNPEAIVL121DIDYKSGTPM131QSAAKAPYLA141KFKVKRCGVS
151-200151ELEKEGLRCR161SDSEDECSTQ171EADGQKISWQ181AAIFKVGDDC191RQDMLALQII
201-250201DLFKNIFQLV211GLDLFVFPYR221VVATAPGCGV231IECIPDCTSR241DQLGRQTDFG
251-300251MYDYFTRQYG261DEALSAQARY271NFIRSMAAYS281LLLFLLQIKD291RHNGNIMLDK
301-350301KGHIIHIDFG311FMFESSPGGN321LGWEPDIKLT331DEMVMIMGGK341MEATPFKWFM
351-400351EMCVRGYLAV361RPYMDAVVSL371VTLMLDTGLP381CFRGQTIKLL391KHRFSPNMTE
401-435401REAANFIMKV411IQSCFLSNRS421RTYDMIQYYQ431NDIPY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
96 - - -
Deep-Palm: 0.98
109 - - -
Deep-Palm: 0.89
147 - - -
Deep-Palm: 0.98
159 - - -
Deep-Palm: 0.96
167 - - -
Deep-Palm: 0.92
190 - - -
Deep-Palm: 0.22
228 - - -
Deep-Palm: 0.67
233 - - -
Deep-Palm: 0.65
237 - - -
Deep-Palm: 0.57
353 - - -
Deep-Palm: 0.58
381 - - -
Deep-Palm: 0.97
414 - -
cerebral cortex (36430497)
Deep-Palm: 0.28
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
95 C → R 0.002545 SNP Missense Mutation GBM
268 R → C 0.002020 SNP Missense Mutation PRAD
394 S → C 0.002427 SNP Missense Mutation BLCA
434 R → C 0.001887 SNP Missense Mutation UCEC
491 R → C 0.002506 SNP Missense Mutation COAD
493 C → S 0.005435 SNP Missense Mutation ESCA
662 C → C 0.001887 SNP Silent UCEC
705 C → C 0.002141 SNP Silent SKCM
865 R → C 0.007299 SNP Missense Mutation READ
892 Y → C 0.007299 SNP Missense Mutation READ
1128 R → C 0.002288 SNP Missense Mutation STAD
1128 R → C 0.001887 SNP Missense Mutation UCEC
1131 C → Y 0.002288 SNP Missense Mutation STAD
1146 R → C 0.002506 SNP Missense Mutation COAD
1148 R → C 0.001887 SNP Missense Mutation UCEC
1159 F → C 0.001887 SNP Missense Mutation UCEC
1164 G → C 0.002288 SNP Missense Mutation STAD
1236 W → C 0.001764 SNP Missense Mutation LUAD
1375 R → C 0.002427 SNP Missense Mutation BLCA
1387 S → C 0.001764 SNP Missense Mutation LUAD
1401 R → C 0.001887 SNP Missense Mutation UCEC
1574 R → C 0.002427 SNP Missense Mutation BLCA
1611 C → W 0.001014 SNP Missense Mutation BRCA
1611 C → Y 0.002288 SNP Missense Mutation STAD
1898 C → Y 0.001764 SNP Missense Mutation LUAD
1917 Y → C 0.002747 SNP Missense Mutation LIHC
2024 Y → C 0.001969 SNP Missense Mutation HNSC
2050 R → C 0.001887 SNP Missense Mutation UCEC
2081 C → R 0.001887 SNP Missense Mutation UCEC
435* C → ? 0.001887 SNP Nonsense Mutation UCEC