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UniProt ID Gene Symbol Protein Name Organism Length Action
A8MU75 PMP22 Peripheral myelin protein 22 Homo sapiens (Human) 118 aa

Protein Details: A8MU75 (PMP22)

Protein Information
AccessionA8MU75
Protein NamesPeripheral myelin protein 22
Gene SymbolPMP22
OrganismHomo sapiens (Human)
Length118 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLLLLLSIIV11LHVAVLVLLF21VSTIVSQWIV31GNGHATDLWQ41NCSTSSSGNV
51-10051HHCFSSSPNE61WLQSVQATMI71LSIIFSILSL81FLFFCQLFTL91TKGGRFYITG
101-118101IFQILAESNS111SQMCGYRD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
42 PMP-22/EMP/MP20/Claudin - -
Deep-Palm: 0.04
53 - - -
Deep-Palm: 0.10
85 SWISSPALM DBPTM CYSMODDB PMP-22/EMP/MP20/Claudin family - -
GPS-Palm: 0.93
Deep-Palm: 0.91
114 - - -
GPS-Palm: 0.90
Deep-Palm: 0.02
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
124 W → C 0.001764 SNP Missense Mutation LUAD
159 R → C 0.001969 SNP Missense Mutation HNSC
159 R → C 0.001887 SNP Missense Mutation UCEC